Gene Symbol | CCT3 |
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Entrez Gene | 7203 |
Alt Symbol | CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5 |
Species | Human |
Gene Type | protein-coding |
Description | chaperonin containing TCP1, subunit 3 (gamma) |
Other Description | T-complex protein 1 subunit gamma|T-complex protein 1, gamma subunit|TCP1 (t-complex-1) ring complex, polypeptide 5|hTRiC5 |
Swissprots | Q9BR64 P49368 Q5SZY1 A6NE14 |
Accessions | EAW52967 P49368 AB208882 BAD92119 AK126400 BAG54323 AK293477 BAG56968 AK300765 BAG62430 AK308023 AK315923 BAH14294 AK316387 BAH14758 AL518070 AL833197 CAI46192 AY524046 AAS94255 BC006501 AAH06501 BC008019 AAH08019 BG476176 BG746513 DQ893014 ABM83940 DQ896259 ABM87258 U17104 AAC50068 X74801 CAA52808 NM_001008800 NP_001008800 NM_005998 NP_005989 NR_036564 NR_036565 NM_001008883 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cytoplasm. |
TCP-1 γ CRISPR/Cas9 KO Plasmid (h) - sc-403203 from Santa Cruz Biotechnology
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TCP-1 γ HDR Plasmid (h) - sc-403203-HDR from Santa Cruz Biotechnology
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TCP-1 γ Double Nickase Plasmid (h) - sc-403203-NIC from Santa Cruz Biotechnology
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TCP-1 γ Double Nickase Plasmid (h2) - sc-403203-NIC-2 from Santa Cruz Biotechnology
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TCP-1 γ CRISPR Activation Plasmid (h) - sc-403203-ACT from Santa Cruz Biotechnology
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TCP-1 γ CRISPR Activation Plasmid (h2) - sc-403203-ACT-2 from Santa Cruz Biotechnology
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TCP-1 γ Lentiviral Activation Particles (h) - sc-403203-LAC from Santa Cruz Biotechnology
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TCP-1 γ Lentiviral Activation Particles (h2) - sc-403203-LAC-2 from Santa Cruz Biotechnology
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TCP-1 γ siRNA (h) - sc-36623 from Santa Cruz Biotechnology
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TCP-1 γ shRNA Plasmid (h) - sc-36623-SH from Santa Cruz Biotechnology
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TCP-1 γ shRNA (h) Lentiviral Particles - sc-36623-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU130371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5666 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5666 from Sigma-Aldrich
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CCT3 siRNA (Human) - CRH4941 from Cohesion Biosciences
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CCT3 - MBS8216899 from MyBioSource
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TCP-1 γ HDR Plasmid (h2) - sc-403203-HDR-2 from Santa Cruz Biotechnology
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TCP-1 γ CRISPR/Cas9 KO Plasmid (h2) - sc-403203-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human CCT3 (NM_005998.4) - SHH258317 from Creative biogene
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Human CCT3 siRNA - orb265443 from Biorbyt
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CCT3 shRNA Plasmid (Human) - CHH4941 from Cohesion Biosciences
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CCT3 miRNA 3'UTR clone - MiUTR3H-03140 from Creative biogene
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CCT3 miRNA 3'UTR clone - MiUTR3H-03141 from Creative biogene
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