ACSL5

Gene Symbol	ACSL5
Entrez Gene	51703
Alt Symbol	ACS2, ACS5, FACL5
Species	Human
Gene Type	protein-coding
Description	acyl-CoA synthetase long-chain family member 5
Other Description	FACL5 for fatty acid coenzyme A ligase 5|LACS 5|fatty acid coenzyme A ligase 5|fatty-acid-Coenzyme A ligase, long-chain 5|long-chain acyl-CoA synthetase 5|long-chain fatty acid coenzyme A ligase 5|long-chain-fatty-acid--CoA ligase 5
Swissprots	Q9UIU4 D3DRB3 Q6UX44 A6GV77 Q9ULC5
Accessions	BAA86054 CAC79123 CAJ56749 EAW49532 EAW49533 EAW49534 EAW49535 EAW49536 EAW49537 EAW49538 EAW49539 Q9ULC5 AB033899 BAA85979 AJ496489 CAD43000 AK000339 AK024932 AK222782 AK223288 AK301786 BAG63242 AK310436 AL708480 AM262166 CAK18174 AY358520 AAQ88884 BC007985 AAH07985 CD689921 CF595490 DQ893266 ABM84192 DQ896596 ABM87595 NM_016234 NP_057318 NM_203379 NP_976313 NM_203380 NP_976314
Function	Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells. {ECO:0000250, ECO:0000269|PubMed:17681178, ECO:0000269|PubMed:18806831, ECO:0000269|PubMed:19459852}.
Subcellular Location	Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Top Pathways	Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACSL5 full length protein - ab162640 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ACSL5 protein fragment - ab162641 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ACS5 / ACSL5 Antibody Blocking Peptide - LS-E17129 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACS5 / ACSL5 Antibody Blocking Peptide - LS-E26096 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ACSL5 Protein - H00051703-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ACSL5 Protein - H00051703-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ACSL5 blocking peptide - GTX89348-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Goat anti ACSL5 antibody Immunizing peptide - orb15110 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

ACSL5 Blocking Peptide - 33R-1075 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACSL5 Peptide - AC21-0924-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ACSL5 - H00051703-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ACSL5 - H00051703-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ACSL5 - H00051703-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACSL5 - H00051703-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ACSL5 Peptide - 45-197P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ACSL5 fusion protein - ag8260 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ACSL5 fusion protein - Ag8258 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Long-chain-fatty-acid--CoA ligase 5(ACSL5) - CSB-YP891734HU CSB-EP891734HU CSB-BP891734HU CSB-MP891734HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACSL5 Protein - abx164528 from Abbexa Category Protein Species Human, Rat

ACSL5 (transcript variant 2) - TP313380 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL5 (transcript variant 3) - TP318932 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL5, Peptide - MBS425941 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Homo sapiens (Human) Long-chain-fatty-acid--CoA ligase 5 - CSB-EP891734HU from Cusabio Category Protein Source E.coli Species Human

ACSL5-FACL5-Antibody-N-term-Blocking-peptide - BP2536a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL5 Peptide, Human - M34GP00172H from Creative Peptides Category Peptide Source Synthetic. Species Human

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