| Gene Symbol | GK |
|---|---|
| Entrez Gene | 2710 |
| Alt Symbol | GK1, GKD |
| Species | Human |
| Gene Type | protein-coding |
| Description | glycerol kinase |
| Other Description | ATP:glycerol 3-phosphotransferase|glycerokinase |
| Swissprots | Q9UMP0 Q8IVR5 Q6IQ27 A6NJP5 Q9UMP1 P32189 B2R833 |
| Accessions | CAB54857 CAB54858 CAB54859 CBG03251 CBG09940 CBV16771 CBV23462 EAW99053 EAW99054 EAW99055 EAW99056 P32189 AA689298 AK294304 BAG57585 AK294938 BAG58015 AK308238 AK313215 BAG36030 AW300142 BC018009 BC037549 AAH37549 BC042421 AAH42421 BC071595 AAH71595 BG400692 BM906503 BX647604 CD369459 DQ891580 ABM82506 DQ894773 ABM85699 L13943 AAA52576 X68285 CAA48346 X69886 CAA49512 XM_005274488 XP_005274545 XM_006724483 XP_006724546 XM_006724484 XP_006724547 XM_006724485 XP_006724548 XM_006724486 XP_006724549 XM_011545491 XP_011543793 XM_011545492 XP_011543794 XM_011545493 XP_011543795 XM_011545494 XP_011543796 NM_000167 NP_000158 NM_001128127 NP_001121599 NM_001205019 NP_001191948 NM_203391 NP_976325 |
| Function | Key enzyme in the regulation of glycerol uptake and metabolism. |
| Subcellular Location | Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm. |
| Tissue Specificity | Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver. |
| Top Pathways | PPAR signaling pathway, Glycerolipid metabolism |