| Gene Symbol |
SEMA3A
|
| Entrez Gene |
395825
|
| Alt Symbol |
COLL-1
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
|
| Other Description |
collapsin|collapsin-1|semaphorin-3A
|
| Swissprots |
Q90607
|
| Accessions |
Q90607 U02528 AAC59638 NM_204977 NP_990308
|
| Function |
Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to neuropilin.
|
| Subcellular Location |
Secreted {ECO:0000250}.
|
| Tissue Specificity |
Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts.
|
