Gene Symbol | OXA1L |
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Entrez Gene | 5018 |
Alt Symbol | OXA1 |
Species | Human |
Gene Type | protein-coding |
Description | oxidase (cytochrome c) assembly 1-like |
Other Description | OXA1-like protein|OXA1Hs|hsa|mitochondrial inner membrane protein OXA1L|oxidase assembly 1-like protein |
Swissprots | Q15070 B4DPA2 |
Accessions | CAA05127 EAW66249 Q15070 AK294849 BAG57953 AK298249 BAG60514 BC001669 AAH01669 BC112331 AAI12332 BP303816 BP330984 BQ029315 BX248001 CAD62333 BX248295 CAD62623 X80695 CAA56712 NM_005015 NP_005006 |
Function | Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria. {ECO:0000269|PubMed:17936786, ECO:0000269|PubMed:7991568}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:17936786}; Multi-pass membrane protein {ECO:0000269|PubMed:17936786}. |
Top Pathways | Protein export |
OXA1L CRISPR/Cas9 KO Plasmid (h) - sc-410921 from Santa Cruz Biotechnology
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OXA1L HDR Plasmid (h) - sc-410921-HDR from Santa Cruz Biotechnology
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OXA1L Double Nickase Plasmid (h) - sc-410921-NIC from Santa Cruz Biotechnology
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OXA1L Double Nickase Plasmid (h2) - sc-410921-NIC-2 from Santa Cruz Biotechnology
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OXA1L CRISPR Activation Plasmid (h) - sc-410921-ACT from Santa Cruz Biotechnology
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OXA1L CRISPR Activation Plasmid (h2) - sc-410921-ACT-2 from Santa Cruz Biotechnology
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OXA1L Lentiviral Activation Particles (h) - sc-410921-LAC from Santa Cruz Biotechnology
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OXA1L Lentiviral Activation Particles (h2) - sc-410921-LAC-2 from Santa Cruz Biotechnology
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OXA1L siRNA (h) - sc-92306 from Santa Cruz Biotechnology
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OXA1L shRNA Plasmid (h) - sc-92306-SH from Santa Cruz Biotechnology
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OXA1L shRNA (h) Lentiviral Particles - sc-92306-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU074341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16213 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16213 from Sigma-Aldrich
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OXA1L siRNA (Human) - CRH3332 from Cohesion Biosciences
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shRNA set against Human OXA1 (NM_005015.3) - SHH369276 from Creative biogene
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Human OXA1L siRNA - orb263834 from Biorbyt
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OXA1L shRNA Plasmid (Human) - CHH3332 from Cohesion Biosciences
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OXA1L miRNA 3'UTR clone - MiUTR3H-03856 from Creative biogene
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