| Gene Symbol |
PPP1R3A
|
| Entrez Gene |
5506
|
| Alt Symbol |
GM, PP1G, PPP1R3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 1, regulatory subunit 3A
|
| Other Description |
RG1|glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle|glycogen-associated regulatory subunit of protein phosphatase-1|protein phosphatase 1 glycogen- associated regulatory subunit|protein phosphatase 1 glycogen-associated regulatory subunit|protein phosphatase 1 regulatory subunit 3A|protein phosphatase 1 regulatory subunit GM|protein phosphatase 1, regulatory (inhibitor) subunit 3A|protein phosphatase type-1 glycogen targeting subunit|serine /threonine specific protein phosphatase|type-1 protein phosphatase skeletal muscle glycogen targeting subunit
|
| Swissprots |
Q7KYM8 Q75LN8 O43476 Q86UI6 A0AVQ2 Q16821 A4D0T6
|
| Accessions |
AAB94596 AAP22361 AAS07492 EAL24370 EAW83477 EAW83478 Q16821 AF024579 AAB94597 BC017405 BC056666 BC070313 BC111452 AAI11453 BC126451 AAI26452 BC126453 AAI26454 BF576879 DB527300 HQ258594 ADR83347 X78578 CAA55316 XM_005250473 XP_005250530 NM_002711 NP_002702
|
| Function |
Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Skeletal muscle and heart. {ECO:0000269|PubMed:9726244}.
|
| Top Pathways |
Insulin signaling pathway
|