| Gene Symbol |
CLDN23
|
| Entrez Gene |
137075
|
| Alt Symbol |
CLDNL, hCG1646163
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 23
|
| Other Description |
2310014B08Rik|claudin-23
|
| Swissprots |
Q08AJ3 Q96B33
|
| Accessions |
EAW65564 Q96B33 AK123547 BAC85642 BC016047 BC125148 AAI25149 BC125149 AAI25150 Z36835 NM_194284 NP_919260
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in germinal center B-cells, placenta, stomach as well as in colon tumor. {ECO:0000269|PubMed:12736707}.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|