CHRNA1

Gene Symbol CHRNA1
Entrez Gene 1134
Alt Symbol ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 1 (muscle)
Other Description acetylcholine receptor subunit alpha|acetylcholine receptor, nicotinic, alpha 1 (muscle)|cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)|muscle nicotinic acetylcholine receptor|nicotinic acetylcholine receptor alpha subunit|nicotinic cholinergic receptor alpha 1
Swissprots D3DPE8 B4DRV6 P02708
Accessions AAY14687 CAA26344 CAA34960 CAA49705 EAX11124 EAX11125 EAX11126 EAX11127 EAX11128 P02708 AK291338 BAF84027 AK299445 BAG61418 AK315312 BAG37716 BC006314 BC043196 BG828551 CD013889 DQ323657 ABD27888 DQ323658 ABD27889 S77094 AAD14247 Y00762 CAA68731 NM_000079 NP_000070 NM_001039523 NP_001034612
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Top Pathways Neuroactive ligand-receptor interaction

AChRα (D6) - sc-32253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AChRα (D6): sc-32253. Indirect FCM analysis of TE 671 cells stained with AChRα (D6), followed by biotin-conjugated goat anti-mouse IgG<sub>2a</sub>: sc-2073, then Avidin-PE: sc-2876. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

AChRα (G10) - sc-32252 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of AChR complex expression in IMR-32 whole cell lysate (A) and in IMR-32 whole cell lysate immunoprecipitated with AChRα (G10): sc-32252 (B) and AChRα (D6): sc-32253 (C) and detected with AChRβ1 (H-101): sc-11371.

AChRα1 (C-18) - sc-1442 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AChRα1 (C-18): sc-1442. Western blot analysis of AChRα1 expression in non-transfected: sc-117752 (A) and human AChRα1 transfected: sc-158225 (B) 293T whole cell lysates.

AChRα1 (61) - sc-58602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AChRα1 (64) - sc-65824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AChRα1 (198) - sc-65836 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AChRα1 (207) - sc-65838 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AChRα1 (H-81) - sc-292790 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AChRα1 (H-81): sc-292790. Western blot analysis of AChRα1 expression in mouse skeletal muscle tissue extract.

AChRα1/3/5 (210) - sc-58603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AChRα1/3/5 (35) - sc-58604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

Anti-Nicotinic Acetylcholine Receptor alpha 1 antibody - ab197172 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human fetal tonsil tisse labelling Nicotinic Acetylcholine Receptor alpha 1 with ab197172 at a dilution of 1/100.

Anti-Nicotinic Acetylcholine Receptor alpha 1 antibody - ab135272 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human prostate carcinoma tissue labelling Nicotinic Acetylcholine Receptor alpha 1 with ab135272 at 1/50.

Anti-Nicotinic Acetylcholine Receptor alpha 1 antibody [61] - ab24631 from Abcam

Prices $370.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 61

Anti-CHRNA1 Antibody - LS-C153364 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (N-Terminus) - LS-C122241 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody - LS-C144728 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (aa25-74) - LS-C19162 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-CHRNA1 Antibody (N-Terminus) - LS-C19277 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Kidney Lysate

Anti-CHRNA1 Antibody (N-Terminus, Sepharose) - LS-C171636 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (N-Terminus, Magnetic beads) - LS-C171635 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (N-Terminus, Sepharose) - LS-C171945 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (N-Terminus, Magnetic beads) - LS-C171944 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (clone 993630) - LS-C195348 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 993630

Anti-CHRNA1 Antibody (Biotin) - LS-C317310 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA1 Antibody (FITC) - LS-C317311 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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