Gene Symbol |
ATP2C1
|
Entrez Gene |
27032
|
Alt Symbol |
ATP2C1A, BCPM, HHD, PMR1, SPCA1, hSPCA1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ATPase, Ca++ transporting, type 2C, member 1
|
Other Description |
ATP-dependent Ca(2+) pump PMR1|ATPase 2C1|ATPase, Ca(2+)-sequestering|HUSSY-28|calcium-transporting ATPase type 2C member 1|secretory pathway Ca2+/Mn2+ ATPase 1
|
Swissprots |
Q8N6V1 G8JLN9 Q86V73 B2RAT7 B4DSW3 G3XAH8 O76005 Q8NCJ7 P98194 B7Z3X9 Q86V72
|
Accessions |
CBG22382 CBV35543 EAW79217 EAW79218 EAW79219 EAW79220 P98194 AB037768 BAA92585 AB209265 BAD92502 AF181120 AAF26295 AF181121 AAF26296 AF189723 AAF27813 AF225981 AAF35375 AJ010953 CAA09425 AK001684 BAA91835 AK074692 BAC11142 AK296470 BAH12365 AK299945 BAG61775 AK304175 BAG65057 AK304374 BAG65212 AK314342 BAG36984 AL833453 AY268374 AAP30008 AY268375 AAP30009 BC028139 AAH28139 BF669202 BF675663 BQ220831 BU188061 DA405579 DC343471 DC345627 DC422788 EU176250 ABW03701 XM_005247354 XP_005247411 XM_005247355 XP_005247412 XM_005247356 XP_005247413 XM_005247357 XP_005247414 XM_005247358 XP_005247415 XM_006713585 XP_006713648 XM_011512685 XP_011510987 XM_011512686 XP_011510988 XM_011512687 XP_011510989 NM_001001485 NP_001001485 NM_001001486 NP_001001486 NM_001001487 NP_001001487 NM_001199179 NP_001186108 NM_001199180 NP_001186109 NM_001199181 NP_001186110 NM_001199182 NP_001186111 NM_001199183 NP_001186112 NM_001199184 NP_001186113 NM_001199185 NP_001186114 NM_014382 NP_055197
|
Function |
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:12707275}; Multi-pass membrane protein {ECO:0000269|PubMed:12707275}.
|
Tissue Specificity |
Found in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney.
|