POLR2J

Gene Symbol POLR2J
Entrez Gene 5439
Alt Symbol POLR2J1, RPB11, RPB11A, RPB11m, hRPB14
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
Other Description DNA-directed RNA polymerase II subunit J-1|DNA-directed RNA polymerase II subunit RPB11-a|RNA polymerase II 13.3 kDa subunit|RNA polymerase II subunit B11-a
Swissprots O43375 A5D6V8 P52435
Accessions CAC18368 P52435 AK290515 BAF83204 BC024165 AAH24165 BC040116 BC065711 AAH65711 BC139902 AAI39903 BC141830 AAI41831 BM545237 BM791979 DQ893151 ABM84077 DQ896446 ABM87445 L37127 AAD05361 X82385 CAA57785 X98433 CAA67075 XM_005250452 XP_005250509 NM_006234 NP_006225
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9852112}.
Tissue Specificity Ubiquitously expressed. High expression was found in heart and skeletal muscle. {ECO:0000269|PubMed:11747469}.
Top Pathways Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

POLR2J1/2/3 (G-2) - sc-514129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
POLR2J1/2/3 (G-2): sc-514129. Western blot analysis of POLR2J1/2/3 expression in HeLa nuclear extract (A) and A549 (B), Sol8 (C) and L8 (D) whole cell lysates.

POLR2J1/2/3 (E-12) - sc-109854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

POLR2J1/2/3 (I-13) - sc-109855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RNA polymerase II RPB11 antibody - ab123269 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RNA polymerase II RPB11 antibody (ab123269) at 1/100 dilution + A549 cell lysate at 35 µg

Anti-RNA polymerase II RPB11 antibody - ab138087 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RNA polymerase II RPB11 antibody (ab138087) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-POLR2J Antibody (aa86-115, AP) - LS-C223726 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa86-115, APC) - LS-C223727 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa86-115, Biotin) - LS-C223728 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa86-115, Azide-free, HRP) - LS-C223729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (Asp24) - LS-C177828 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of POLR2J1 (D24) pAb in extracts from RAW264.7 cells.

Anti-POLR2J Antibody (aa86-115, PE) - LS-C223730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa86-115, FITC) - LS-C223731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, AP) - LS-C223732 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, APC) - LS-C223733 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, FITC) - LS-C223735 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, Biotin) - LS-C223734 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, Azide-free, HRP) - LS-C223736 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa89-117, PE) - LS-C223737 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa93-117) - LS-C324172 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa87-117) - LS-C324174 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody - LS-C341281 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-POLR2J Antibody (aa24-73) - LS-C200610 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using RPB11 antibody.

Anti-POLR2J Antibody (aa10-59) - LS-C119916 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from RAW264.7 cells, using RPB11 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-POLR2J Antibody (clone 1A10) - LS-C197948 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A10
Western Blot analysis of POLR2J expression in transfected 293T cell line by POLR2J monoclonal antibody (M02), clone 1A10.Lane 1: POLR2J transfected lysate(13.3 KDa).Lane 2: Non-transfected lysate.

Anti-POLR2J Antibody (aa89-117) - LS-C163855 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
POLR2J Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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