| Gene Symbol |
SLC9A8
|
| Entrez Gene |
23315
|
| Alt Symbol |
NHE-8, NHE8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
|
| Other Description |
Na(+)/H(+) exchanger 8|sodium/hydrogen exchanger 8|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 8
|
| Swissprots |
Q9Y2E8 Q9Y507 Q9BX15 B4DTQ8 Q68CZ8 Q2M1U9
|
| Accessions |
CAH05443 EAW75647 EAW75648 EAW75649 EAW75650 EAW75651 EAW75652 Q9Y2E8 AB023156 BAA76783 AK124491 AK131001 BAC85475 AK295665 BAH12147 AK295803 BAG58621 AK295822 BAG58639 AK300318 BAG62070 AK308328 AK310530 AL049469 AL833574 BC112213 AAI12214 BX424838 BX430866 CR749638 CAH18432 XM_006723756 XP_006723819 XM_011528736 XP_011527038 XM_011528737 XP_011527039 XM_011528738 XP_011527040 XM_011528739 XP_011527041 XM_011528740 XP_011527042 XM_011528741 XP_011527043 XM_011528742 XP_011527044 XM_011528743 XP_011527045 XM_011528744 XP_011527046 XM_011528745 XP_011527047 XM_011528746 XP_011527048 NM_001260491 NP_001247420 NM_015266 NP_056081 NR_048537 NR_048538 NR_048539 NR_048540
|
| Function |
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. {ECO:0000269|PubMed:15522866}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:15522866}; Multi-pass membrane protein {ECO:0000269|PubMed:15522866}.
|
| Tissue Specificity |
Ubiquitous. Strongly expressed in skeletal muscle and kidney. {ECO:0000269|PubMed:15522866}.
|
