Gene Symbol | WNT2 |
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Entrez Gene | 7472 |
Alt Symbol | INT1L1, IRP |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family member 2 |
Other Description | Int-1-related protein|int-1-like protein 1|protein Wnt-2|secreted growth factor |
Swissprots | A4D0V1 Q75N05 Q9UDP9 P09544 |
Accessions | AAB67043 AAD28351 CAI38640 CCQ43213 EAL24355 EAW83525 P09544 AK056742 BAG51800 BC029854 AAH29854 BC078170 AAH78170 BT019608 AAV38415 DQ892457 ABM83383 DQ895669 ABM86595 X07876 CAA30725 NM_003391 NP_003382 NR_024047 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. {ECO:0000269|PubMed:11449391}. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Wnt-2 CRISPR/Cas9 KO Plasmid (h) - sc-402665 from Santa Cruz Biotechnology
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Wnt-2 HDR Plasmid (h) - sc-402665-HDR from Santa Cruz Biotechnology
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Wnt-2 Double Nickase Plasmid (h) - sc-402665-NIC from Santa Cruz Biotechnology
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Wnt-2 Double Nickase Plasmid (h2) - sc-402665-NIC-2 from Santa Cruz Biotechnology
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Wnt-2 CRISPR Activation Plasmid (h) - sc-402665-ACT from Santa Cruz Biotechnology
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Wnt-2 CRISPR Activation Plasmid (h2) - sc-402665-ACT-2 from Santa Cruz Biotechnology
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Wnt-2 Lentiviral Activation Particles (h) - sc-402665-LAC from Santa Cruz Biotechnology
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Wnt-2 Lentiviral Activation Particles (h2) - sc-402665-LAC-2 from Santa Cruz Biotechnology
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Wnt-2 siRNA (h) - sc-36841 from Santa Cruz Biotechnology
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Wnt-2 shRNA Plasmid (h) - sc-36841-SH from Santa Cruz Biotechnology
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Wnt-2 shRNA (h) Lentiviral Particles - sc-36841-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22916 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22916 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07127 from Sigma-Aldrich
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WNT2 siRNA (Human) - CRH5111 from Cohesion Biosciences
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WNT2 - MBS8228141 from MyBioSource
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shRNA set against Human WNT2 (NM_003391.2) - SHH447256 from Creative biogene
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Human WNT2 siRNA - orb265613 from Biorbyt
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WNT2 shRNA Plasmid (Human) - CHH5111 from Cohesion Biosciences
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WNT2 miRNA 3'UTR clone - MiUTR3H-01254 from Creative biogene
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