Gene Symbol | MAN2B1 |
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Entrez Gene | 4125 |
Alt Symbol | LAMAN, MANB |
Species | Human |
Gene Type | protein-coding |
Description | mannosidase, alpha, class 2B, member 1 |
Other Description | lysosomal acid alpha-mannosidase|lysosomal alpha-mannosidase|mannosidase alpha-B|mannosidase, alpha B, lysosomal |
Swissprots | Q93094 Q16680 O15330 O00754 Q9BW13 G5E928 |
Accessions | AAC51362 EAW84279 EAW84280 EAW84281 O00754 AB209921 BAD93158 AK291572 BAF84261 AK303418 BAG64471 AU127707 AU128464 AW172353 BC000736 AAH00736 BI828908 BM147968 BM982008 BU659731 DB237901 DQ891878 ABM82804 DQ895066 ABM85992 U05572 AAB03816 U60266 AAC34130 U68382 AAC50811 U68567 AAC50812 XM_005259913 XP_005259970 XM_011528017 XP_011526319 NM_000528 NP_000519 NM_001173498 NP_001166969 |
Function | Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Other glycan degradation |
MAN2B1 CRISPR/Cas9 KO Plasmid (h) - sc-418024 from Santa Cruz Biotechnology
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MAN2B1 HDR Plasmid (h) - sc-418024-HDR from Santa Cruz Biotechnology
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MAN2B1 Double Nickase Plasmid (h) - sc-418024-NIC from Santa Cruz Biotechnology
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MAN2B1 Double Nickase Plasmid (h2) - sc-418024-NIC-2 from Santa Cruz Biotechnology
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MAN2B1 CRISPR Activation Plasmid (h) - sc-418024-ACT from Santa Cruz Biotechnology
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MAN2B1 CRISPR Activation Plasmid (h2) - sc-418024-ACT-2 from Santa Cruz Biotechnology
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MAN2B1 Lentiviral Activation Particles (h) - sc-418024-LAC from Santa Cruz Biotechnology
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MAN2B1 Lentiviral Activation Particles (h2) - sc-418024-LAC-2 from Santa Cruz Biotechnology
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MAN2B1 siRNA (h) - sc-97712 from Santa Cruz Biotechnology
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MAN2B1 shRNA Plasmid (h) - sc-97712-SH from Santa Cruz Biotechnology
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MAN2B1 shRNA (h) Lentiviral Particles - sc-97712-V from Santa Cruz Biotechnology
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MAN2B1 RNAi - H00004125-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12967 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12967 from Sigma-Aldrich
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MAN2B1 siRNA (Human) - CRH2802 from Cohesion Biosciences
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shRNA set against Human MAN2B1 (NM_000528.3) - SHH337323 from Creative biogene
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Human MAN2B1 siRNA - orb263304 from Biorbyt
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MAN2B1 shRNA Plasmid (Human) - CHH2802 from Cohesion Biosciences
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MAN2B1 miRNA 3'UTR clone - MiUTR3H-10618 from Creative biogene
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