| Gene Symbol |
SLC25A11
|
| Entrez Gene |
8402
|
| Alt Symbol |
OGC, SLC20A4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
|
| Other Description |
OGCP|mitochondrial 2-oxoglutarate/malate carrier protein|solute carrier family 20 (oxoglutarate carrier), member 4|solute carrier family 25 member 11
|
| Swissprots |
Q969P7 Q02978 F5GY65 O75537
|
| Accessions |
CAA46905 EAW90389 EAW90390 EAW90391 EAW90392 Q02978 AA937945 AF070548 AAC28637 AK290376 BAF83065 AK313010 BC006508 AAH06508 BC006519 AAH06519 BC016294 AAH16294 BC016473 BC017170 AAH17170 BI752999 BM047391 CB155476 CR456834 CAG33115 DQ891152 ABM82078 DQ894331 ABM85257 NM_001165417 NP_001158889 NM_001165418 NP_001158890 NM_003562 NP_003553
|
| Function |
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
|
| Subcellular Location |
Mitochondrion inner membrane; Multi-pass membrane protein.
|
![Western Blot: SLC25A11 Overexpression Lysate (Adult Normal) [NBL1-16047] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC25A11.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2775_SLC25A11%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16047-img0002.jpg)