Ehd2

Gene Symbol Ehd2
Entrez Gene 259300
Alt Symbol BC027084, C130052H20Rik
Species Mouse
Gene Type protein-coding
Description EH-domain containing 2
Other Description EH domain-containing protein 2
Swissprots Q8BL28 Q8BH64
Accessions EDL42114 EDL42115 Q8BH64 AK029240 AK029557 AK031203 BAC27298 AK046566 BAC32789 AK048356 BAC33310 AK050243 BAC34142 AK084455 BAC39188 AK085016 BAC39339 AY531389 AAS48536 BC020014 AAH20014 BC027084 AAH27084 BC031731 BC113161 AAI13162 XM_011250582 XP_011248884 NM_153068 NP_694708
Function Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP. {ECO:0000269|PubMed:14676205, ECO:0000269|PubMed:18502764, ECO:0000269|PubMed:21177873}.
Subcellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes.
Tissue Specificity Detected in lung and adipocytes. Detected at lower levels in heart and skeletal muscle. {ECO:0000269|PubMed:14676205}.
Top Pathways Endocytosis

EHD2 CRISPR/Cas9 KO Plasmid (m) - sc-435199 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 HDR Plasmid (m) - sc-435199-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 Double Nickase Plasmid (m) - sc-435199-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 Double Nickase Plasmid (m2) - sc-435199-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 CRISPR Activation Plasmid (m) - sc-435199-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 CRISPR Activation Plasmid (m2) - sc-435199-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 Lentiviral Activation Particles (m) - sc-435199-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 Lentiviral Activation Particles (m2) - sc-435199-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

EHD2 siRNA (m) - sc-40518 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

EHD2 shRNA Plasmid (m) - sc-40518-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

EHD2 shRNA (m) Lentiviral Particles - sc-40518-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU018101 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN30502 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30502 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EHD2 siRNA (Mouse) - CRN3936 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

EHD2 - MBS8239712 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse EHD2 (NM_153068.3) - SHH283989 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Ehd2(NM_153068.3) - SHH027587 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse EHD2 siRNA - orb293411 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

EHD2 shRNA Plasmid (Mouse) - CHN3936 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

EHD2 miRNA 3'UTR clone - MiUTR1M-04296 from Creative biogene

Species Reactivities Mouse
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