Gene Symbol |
CARKD
|
Entrez Gene |
55739
|
Alt Symbol |
LP3298
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
carbohydrate kinase domain containing
|
Other Description |
ATP-dependent (S)-NAD(P)H-hydrate dehydratase|ATP-dependent NAD(P)HX dehydratase|carbohydrate kinase domain-containing protein
|
Swissprots |
Q8IW45 Q9H7W1 Q9NVF5 B4DXT4 Q5T9X3
|
Accessions |
EAX09114 EAX09115 EAX09116 EAX09117 EAX09118 EAX09119 EAX09120 EAX09121 EAX09122 EAX09123 EAX09124 EAX09125 Q8IW45 AF091088 AAC72957 AF151071 AAF36157 AK001631 BAA91797 AK024260 BAB14863 AK057767 AK058043 AK091867 AK093771 BAG52761 AK225129 AK296227 BAH12286 AK296758 BAG59339 AK298917 BAG61023 AK302117 BAG63496 BC005150 BC006416 BC041028 AAH41028 BQ955656 DA175011 DA435066 DA815628 NM_001242881 NP_001229810 NM_001242882 NP_001229811 NM_001242883 NP_001229812 NM_018210 NP_060680 NR_040103 NR_040104
|
Function |
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. {ECO:0000255|HAMAP-Rule:MF_03157}.
|
Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03157}.
|