Gene Symbol | OVOL2 |
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Entrez Gene | 58495 |
Alt Symbol | EUROIMAGE566589, ZNF339 |
Species | Human |
Gene Type | protein-coding |
Description | ovo-like zinc finger 2 |
Other Description | transcription factor Ovo-like 2|zinc finger protein 339 |
Swissprots | Q9Y4M0 Q9BX22 Q5T8B4 Q9BRP0 Q9HA54 |
Accessions | EAX10258 EAX10259 Q9BRP0 AI811832 AK022284 BAB14002 AL079276 CAB45151 BC006148 AAH06148 BE791524 BM563561 BT007295 AAP35959 BX331154 DB460914 NM_001303461 NP_001290390 NM_001303462 NP_001290391 NM_021220 NP_067043 |
Function | Zinc-finger transcription repressor factor. Plays a critical role to maintain the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition mainly through the up-regulation of ZEB1 expression. Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1. {ECO:0000250, ECO:0000269|PubMed:19700410}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in testis, ovary, heart and skeletal muscle. {ECO:0000269|PubMed:12213202}. |
Human OVOL2 full length protein - ab163682 from Abcam
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OVOL2 Antibody Blocking Peptide - LS-E14284 from LifeSpan Bioscience
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OVOL2 Antibody Blocking Peptide - LS-E11708 from LifeSpan Bioscience
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Recombinant Human OVOL2 Protein - H00058495-P02 from Novus Biologicals
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OVOL2-Antibody-N-term-Blocking-Peptide - BP19600a from Abgent, a WuXi AppTec company
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OVOL2 / ZNF339 - H00058495-P02 from Acris Antibodies
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OVOL2 / ZNF339 - H00058495-P02-10 from Acris Antibodies
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OVOL2 / ZNF339 - H00058495-P02-25 from Acris Antibodies
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Recombinant Human Transcription factor Ovo-like 2(OVOL2) - CSB-YP887110HU CSB-EP887110HU CSB-BP887110HU CSB-MP887110HU from Cusabio
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OVOL2 Recombinant Protein Antigen - NBP1-88754PEP from Novus Biologicals
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OVOL2 Peptide, Human - M34GP11183H from Creative Peptides
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