Gene Symbol | NT5C3B |
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Entrez Gene | 115024 |
Alt Symbol | NT5C3L |
Species | Human |
Gene Type | protein-coding |
Description | 5'-nucleotidase, cytosolic IIIB |
Other Description | 5'-nucleotidase, cytosolic III-like|7-methylguanosine nucleotidase|7-methylguanosine phosphate-specific 5'-nucleotidase|N(7)-methylguanylate 5'-phosphatase|cN-III-like protein|cytosolic 5'-nucleotidase 3B|cytosolic 5'-nucleotidase III-like protein |
Swissprots | Q969T7 A8MWB9 Q7L3B7 C9JKC4 |
Accessions | EAW60771 EAW60772 EAW60773 Q969T7 AA730137 BC013742 AAH13742 BC014132 AAH14132 BC016971 AAH16971 BC067788 AAH67788 BE296438 BF339623 BI914049 BI917511 BX365588 BX438861 BX460247 CB045324 CN393115 DR159341 HQ447126 ADQ31613 R61279 XM_006721668 XP_006721731 XM_006721669 XP_006721732 XM_006721670 XP_006721733 XM_011524276 XP_011522578 XM_011524277 XP_011522579 NM_052935 NP_443167 NR_033464 NR_033465 |
Function | Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate. The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids. Also has weak activity for CMP. UMP and purine nucleotides are poor substrates. {ECO:0000269|PubMed:23223233}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Top Pathways | Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism |
Human NT5C3L full length protein - ab187423 from Abcam
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NT5C3B / NT5C3L Antibody Blocking Peptide - LS-E2325 from LifeSpan Bioscience
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NT5C3B / NT5C3L Antibody Blocking Peptide - LS-E30243 from LifeSpan Bioscience
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NT5C3L-Antibody-N-term-Blocking-peptide - BP13283a from Abgent, a WuXi AppTec company
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NT5C3B protein (His tag) - 80R-4022 from Fitzgerald
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NT5C3L (1-300, His-tag) - AR51707PU-N from Acris Antibodies
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NT5C3L (1-300, His-tag) - AR51707PU-S from Acris Antibodies
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NT5C3L fusion protein - Ag9458 from Proteintech Group
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NT5C3L fusion protein - Ag9441 from Proteintech Group
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Recombinant Human 5'-nucleotidase, cytosolic IIIB, His-tagged - NT5C3B-664H from Creative Biomart
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Recombinant Human NT5C3L, GST-tagged - NT5C3L-1383H from Creative Biomart
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Recombinant Human Cytosolic 5'-nucleotidase III-like protein(NT5C3L) - CSB-YP853374HU CSB-EP853374HU CSB-BP853374HU CSB-MP853374HU from Cusabio
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NT5C3B, 1-300aa, Human, His tag, E.coli - ATGP2887 from ATGen
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NT5C3L - TP304354 from Acris Antibodies
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NT5C3L Protein - NBP1-93511PEP from Novus Biologicals
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NT5C3L Recombinant Protein Antigen - NBP2-38818PEP from Novus Biologicals
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5'-Nucleotidase, Cytosolic IIIB, Recombinant Protein - MBS140809 from MyBioSource
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NT5C3B, human recombinant - P1040-20 from Biovision
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NT5C3B, human recombinant - P1040-100 from Biovision
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NT5C3L Recombinant Protein - NBP2-51896 from Novus Biologicals
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5'-Nucleotidase, Cytosolic IIIB, Human Recombinant - 228-20781-1 from RayBiotech
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NT5C3B - PAT-82886-1 from Nordic BioSite
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NT5C3B - PAT-82886-2 from Nordic BioSite
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NT5C3B, human recombinant - P1040 from Biovision
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NT5C3B, Human recombinant - 268-11543-1 from RayBiotech
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