| Gene Symbol |
KRTAP19-1
|
| Entrez Gene |
337882
|
| Alt Symbol |
KAP19.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 19-1
|
| Other Description |
high tyrosine-glycine keratin-associated protein 19.1|keratin-associated protein 19-1
|
| Swissprots |
Q3LI75 A4QN27 Q8IUB9
|
| Accessions |
EAX09898 Q8IUB9 AB096943 BAE46358 AJ457067 CAD29723 BC126284 AAI26285 BC126286 AAI26287 BC146600 AAI46601 BC148506 AAI48507 NM_181607 NP_853638
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Detected in the upper portion of the hair cortex.
|