Gene Symbol |
AREG
|
Entrez Gene |
374
|
Alt Symbol |
AR, AREGB, CRDGF, SDGF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
amphiregulin
|
Other Description |
amphiregulin B|colorectum cell-derived growth factor|schwannoma-derived growth factor
|
Swissprots |
P15514 Q5U026
|
Accessions |
AAA51773 AAR05438 EAX05710 P15514 AK023449 AW014754 BC009799 AAH09799 BC146953 AAI46954 BC146967 AAI46968 BT019866 AAV38669 DQ892890 ABM83816 DQ896137 ABM87136 HY047499 M30704 AAA51781 NM_001657 NP_001648
|
Function |
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
|
Subcellular Location |
Membrane; Single-pass membrane protein.
|
Top Pathways |
ErbB signaling pathway, Hippo signaling pathway
|