AREG

Gene Symbol AREG
Entrez Gene 374
Alt Symbol AR, AREGB, CRDGF, SDGF
Species Human
Gene Type protein-coding
Description amphiregulin
Other Description amphiregulin B|colorectum cell-derived growth factor|schwannoma-derived growth factor
Swissprots P15514 Q5U026
Accessions AAA51773 AAR05438 EAX05710 P15514 AK023449 AW014754 BC009799 AAH09799 BC146953 AAI46954 BC146967 AAI46968 BT019866 AAV38669 DQ892890 ABM83816 DQ896137 ABM87136 HY047499 M30704 AAA51781 NM_001657 NP_001648
Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular Location Membrane; Single-pass membrane protein.
Top Pathways ErbB signaling pathway, Hippo signaling pathway