Gene Symbol | AREG |
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Entrez Gene | 374 |
Alt Symbol | AR, AREGB, CRDGF, SDGF |
Species | Human |
Gene Type | protein-coding |
Description | amphiregulin |
Other Description | amphiregulin B|colorectum cell-derived growth factor|schwannoma-derived growth factor |
Swissprots | P15514 Q5U026 |
Accessions | AAA51773 AAR05438 EAX05710 P15514 AK023449 AW014754 BC009799 AAH09799 BC146953 AAI46954 BC146967 AAI46968 BT019866 AAV38669 DQ892890 ABM83816 DQ896137 ABM87136 HY047499 M30704 AAA51781 NM_001657 NP_001648 |
Function | Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. |
Subcellular Location | Membrane; Single-pass membrane protein. |
Top Pathways | ErbB signaling pathway, Hippo signaling pathway |
Amphiregulin CRISPR/Cas9 KO Plasmid (h) - sc-400987 from Santa Cruz Biotechnology
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Amphiregulin HDR Plasmid (h) - sc-400987-HDR from Santa Cruz Biotechnology
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Amphiregulin Double Nickase Plasmid (h) - sc-400987-NIC from Santa Cruz Biotechnology
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Amphiregulin Double Nickase Plasmid (h2) - sc-400987-NIC-2 from Santa Cruz Biotechnology
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Amphiregulin CRISPR Activation Plasmid (h) - sc-400987-ACT from Santa Cruz Biotechnology
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Amphiregulin CRISPR Activation Plasmid (h2) - sc-400987-ACT-2 from Santa Cruz Biotechnology
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Amphiregulin Lentiviral Activation Particles (h) - sc-400987-LAC from Santa Cruz Biotechnology
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Amphiregulin Lentiviral Activation Particles (h2) - sc-400987-LAC-2 from Santa Cruz Biotechnology
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Amphiregulin siRNA (h) - sc-39412 from Santa Cruz Biotechnology
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Amphiregulin shRNA Plasmid (h) - sc-39412-SH from Santa Cruz Biotechnology
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Amphiregulin shRNA (h) Lentiviral Particles - sc-39412-V from Santa Cruz Biotechnology
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Amphiregulin RNAi - H00000374-R01 from Novus Biologicals
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MISSION® esiRNA - EHU147931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3386 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3386 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02018 from Sigma-Aldrich
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AREG siRNA (Human) - CRH0267 from Cohesion Biosciences
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AREG - MBS8202295 from MyBioSource
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shRNA set against Human AREG(NM_001657.2) - SHG068219 from Creative biogene
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Human AREG siRNA - orb260769 from Biorbyt
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AREG shRNA Plasmid (Human) - CHH0267 from Cohesion Biosciences
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AREG miRNA 3'UTR clone - MiUTR1H-00506 from Creative biogene
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