Gene Symbol | PIGV |
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Entrez Gene | 55650 |
Alt Symbol | GPI-MT-II, HPMRS1, PIG-V |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class V |
Other Description | GPI mannosyltransferase 2|GPI mannosyltransferase II|Ybr004c homolog|dol-P-Man dependent GPI mannosyltransferase |
Swissprots | Q9NX26 Q5JYG7 D3DPL2 Q5JYG9 Q9NUD9 Q5JYG8 |
Accessions | CAD34896 CAH05377 CAH05438 CAH05439 EAX07790 EAX07791 EAX07792 Q9NUD9 AK000484 BAA91196 AK056539 AK097053 AK225521 AK301626 BAG63111 BC013568 AAH13568 BI463967 CX867528 DA280125 NM_001202554 NP_001189483 NM_017837 NP_060307 |
Function | Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. {ECO:0000269|PubMed:15623507, ECO:0000269|PubMed:15720390}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15623507}; Multi-pass membrane protein {ECO:0000269|PubMed:15623507}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-V CRISPR/Cas9 KO Plasmid (h) - sc-418192 from Santa Cruz Biotechnology
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PIG-V HDR Plasmid (h) - sc-418192-HDR from Santa Cruz Biotechnology
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PIG-V Double Nickase Plasmid (h) - sc-418192-NIC from Santa Cruz Biotechnology
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PIG-V Double Nickase Plasmid (h2) - sc-418192-NIC-2 from Santa Cruz Biotechnology
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PIG-V CRISPR Activation Plasmid (h) - sc-418192-ACT from Santa Cruz Biotechnology
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PIG-V CRISPR Activation Plasmid (h2) - sc-418192-ACT-2 from Santa Cruz Biotechnology
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PIG-V Lentiviral Activation Particles (h) - sc-418192-LAC from Santa Cruz Biotechnology
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PIG-V Lentiviral Activation Particles (h2) - sc-418192-LAC-2 from Santa Cruz Biotechnology
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PIG-V siRNA (h) - sc-88579 from Santa Cruz Biotechnology
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PIG-V shRNA Plasmid (h) - sc-88579-SH from Santa Cruz Biotechnology
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PIG-V shRNA (h) Lentiviral Particles - sc-88579-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU033651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16799 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16799 from Sigma-Aldrich
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PIGV siRNA (Human) - CRJ0802 from Cohesion Biosciences
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Human PIGV siRNA - orb271303 from Biorbyt
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PIGV shRNA Plasmid (Human) - CHJ0802 from Cohesion Biosciences
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PIGV miRNA 3'UTR clone - MiUTR3H-11120 from Creative biogene
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