ACOX1

Gene Symbol	ACOX1
Entrez Gene	51
Alt Symbol	ACOX, PALMCOX, SCOX
Species	Human
Gene Type	protein-coding
Description	acyl-CoA oxidase 1, palmitoyl
Other Description	AOX|acyl-CoA oxidase, straight-chain|acyl-Coenzyme A oxidase 1, palmitoyl|palmitoyl-CoA oxidase|peroxisomal acyl-coenzyme A oxidase 1|peroxisomal fatty acyl-CoA oxidase|straight-chain acyl-CoA oxidase
Swissprots	Q9UD31 Q15068 Q15101 A8KAA0 A8K6X8 Q16131 Q7Z3W5 B4DK61 Q12863 F5GYQ8 Q15067
Accessions	AAA19113 AAA19114 CBF60587 CBF65740 CBF73135 CBU85830 CBU90611 CBU96027 EAW89349 EAW89350 EAW89351 EAW89352 Q15067 AK095501 AK225897 AK291793 BAF84482 AK292965 BAF85654 AK296409 BAG59073 AK300447 BAG62169 AK308218 AM393156 CAL38034 BC008767 AAH08767 BC010425 AAH10425 BQ943492 BX537380 CAD97622 DC297086 S69189 AAB30019 U07866 AAA18595 X71440 CAA50574 XM_011524868 XP_011523170 XM_011524869 XP_011523171 NM_001185039 NP_001171968 NM_004035 NP_004026 NM_007292 NP_009223
Function	Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA. {ECO:0000269|PubMed:17458872, ECO:0000269|PubMed:17603022}.
Subcellular Location	Peroxisome.
Tissue Specificity	Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart. {ECO:0000269|PubMed:17603022, ECO:0000269|PubMed:20195242}.
Top Pathways	PPAR signaling pathway, Peroxisome, cAMP signaling pathway, alpha-Linolenic acid metabolism, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACOX1 full length protein - ab114556 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

ACOX1 / ACOX Antibody Blocking Peptide - LS-E6985 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACOX1 / ACOX Antibody Blocking Peptide - LS-E6986 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ACOX1 Protein - H00000051-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ACOX1 Peptide - P1139 from Novus Biologicals Category Peptide Species Human

ACOX1 Peptide - P1138 from Novus Biologicals Category Peptide Species Human

ACOX1-Antibody-C-term-Blocking-Peptide - BP2523b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACOX1-Antibody-N-term-Blocking-Peptide - BP2523a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ACOX1 protein (His Tag) - orb138122 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

ACOX1 - H00000051-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACOX1 - H00000051-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AOX fusion protein - Ag1405 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ACOX1, His tagged - ACOX1-2491H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Human ACOX1 / aox Protein (His Tag) - 11266-H07B-100 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human Peroxisomal acyl-coenzyme A oxidase 1(ACOX1) - CSB-YP617998HU CSB-EP617998HU CSB-BP617998HU CSB-MP617998HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACOX1 Protein - abx164520 from Abbexa Category Protein Species Human, Mouse, Rat

Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1), Recombinant Protein - MBS1307432 from MyBioSource Category Protein Prices $1,460.00, $1,460.00, $1,690.00, $1,690.00, $2,485.00, $2,485.00, $2,925.00, $2,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human ACOX1 / aox Protein (His tag) - PKSH031175 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Human

ACOX1 Recombinant Protein Antigen - NBP1-80951PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACOX1 Recombinant Protein Antigen - NBP1-80950PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACOX1 Recombinant Protein Antigen - NBP1-80949PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACOX1 Peptide, Human - M34GP00150H from Creative Peptides Category Peptide Source Synthetic. Species Human

ACOX1 Recombinant Protein (OPCD00118) - OPCD00118 from Aviva Systems Biology Category Protein Source E.coli Species Human

Human ACOX1 / aox Protein (His Tag) - 11266-H07B from ABclonal Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Baculovirus-Insect Cells Species Human

Recombinant Human Peroxisomal Acyl-coenzyme A Oxidase 1,ACOX1 (N-6His) - AP76364 from Signalway Antibody Category Protein Prices $349.00, $749.00, $2,289.00, $3,489.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source E.coli Species Human

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