| Gene Symbol |
MAOA
|
| Entrez Gene |
100033867
|
| Alt Symbol |
-
|
| Species |
Horse
|
| Gene Type |
protein-coding
|
| Description |
monoamine oxidase A
|
| Other Description |
MAO-A|amine oxidase [flavin-containing] A|monoamine oxidase type A
|
| Swissprots |
Q5NU32
|
| Accessions |
Q5NU32 AB178282 BAD80721 NM_001081832 NP_001075301
|
| Function |
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion outer membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism
|