Gene Symbol | POLE2 |
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Entrez Gene | 5427 |
Alt Symbol | DPE2 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (DNA directed), epsilon 2, accessory subunit |
Other Description | DNA polymerase II subunit 2|DNA polymerase epsilon subunit 2|DNA polymerase epsilon subunit B|polymerase (DNA directed), epsilon 2 (p59 subunit) |
Swissprots | O43560 P56282 A4LBB7 B4DDE6 A6NH58 A4FU92 A0AV55 |
Accessions | AAK72254 ABO43040 EAW65754 P56282 AF025840 AAC51920 AF036899 AAC39610 AK293163 BAG56707 AK314963 BC112962 AAI12963 BC126218 AAI26219 BC126220 AAI26221 BG189206 BX248064 CAD62358 HQ258453 ADR83207 XM_011536841 XP_011535143 XM_011536842 XP_011535144 XM_011536843 XP_011535145 XM_011536844 XP_011535146 XR_943479 XR_943480 NM_001197330 NP_001184259 NM_001197331 NP_001184260 NM_002692 NP_002683 |
Function | Participates in DNA repair and in chromosomal DNA replication. |
Subcellular Location | Nucleus. |
Top Pathways | DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism |
DNA pol ε B siRNA (h) - sc-37781 from Santa Cruz Biotechnology
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DNA pol ε B shRNA Plasmid (h) - sc-37781-SH from Santa Cruz Biotechnology
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DNA pol ε B shRNA (h) Lentiviral Particles - sc-37781-V from Santa Cruz Biotechnology
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DNA Polymerase epsilon p59 RNAi - H00005427-R01 from Novus Biologicals
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MISSION® esiRNA - EHU007601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17095 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17095 from Sigma-Aldrich
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POLE2 siRNA (Human) - CRH3630 from Cohesion Biosciences
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shRNA set against Human Pole2 (NM_002692.3) - SHH379176 from Creative biogene
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Human POLE2 siRNA - orb264132 from Biorbyt
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POLE2 shRNA Plasmid (Human) - CHH3630 from Cohesion Biosciences
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POLE2 miRNA 3'UTR clone - MiUTR3H-05207 from Creative biogene
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