Gene Symbol | LARS2 |
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Entrez Gene | 23395 |
Alt Symbol | LEURS, PRLTS4 |
Species | Human |
Gene Type | protein-coding |
Description | leucyl-tRNA synthetase 2, mitochondrial |
Other Description | leucine tRNA ligase 2, mitochondrial|leucine tRNA ligase 2, mitocondrial|leucine translase|probable leucine--tRNA ligase, mitochondrial|probable leucyl-tRNA synthetase, mitochondrial |
Swissprots | Q15031 |
Accessions | CAC35916 EAW64740 Q15031 AK025465 AK026113 AK308146 BC025989 AAH25989 BI463427 D21851 BAA04877 DQ890553 ABM92170 EU176500 ABW03301 XM_005265006 XP_005265063 XM_011533554 XP_011531856 NM_015340 NP_056155 |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed, but highest expression in tissues with high metabolic rates, such as skeletal muscle, heart, and kidney. {ECO:0000269|PubMed:20194621}. |
Top Pathways | Aminoacyl-tRNA biosynthesis |
LARS2 CRISPR/Cas9 KO Plasmid (h) - sc-409849 from Santa Cruz Biotechnology
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LARS2 HDR Plasmid (h) - sc-409849-HDR from Santa Cruz Biotechnology
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LARS2 Double Nickase Plasmid (h) - sc-409849-NIC from Santa Cruz Biotechnology
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LARS2 Double Nickase Plasmid (h2) - sc-409849-NIC-2 from Santa Cruz Biotechnology
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LARS2 CRISPR Activation Plasmid (h) - sc-409849-ACT from Santa Cruz Biotechnology
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LARS2 CRISPR Activation Plasmid (h2) - sc-409849-ACT-2 from Santa Cruz Biotechnology
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LARS2 Lentiviral Activation Particles (h) - sc-409849-LAC from Santa Cruz Biotechnology
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LARS2 Lentiviral Activation Particles (h2) - sc-409849-LAC-2 from Santa Cruz Biotechnology
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LARS2 siRNA (h) - sc-78462 from Santa Cruz Biotechnology
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LARS2 shRNA Plasmid (h) - sc-78462-SH from Santa Cruz Biotechnology
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LARS2 shRNA (h) Lentiviral Particles - sc-78462-V from Santa Cruz Biotechnology
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LARS2 RNAi - H00023395-R01 from Novus Biologicals
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MISSION® esiRNA - EHU137091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11557 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11557 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12562 from Sigma-Aldrich
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LARS2 siRNA (Human) - CRH8236 from Cohesion Biosciences
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shRNA set against Human LARS2 (NM_015340.3) - SHH328575 from Creative biogene
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shRNA set against Human LARS2(NM_015340.3) - SHH142683 from Creative biogene
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Human LARS2 siRNA - orb268738 from Biorbyt
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LARS2 shRNA Plasmid (Human) - CHH8236 from Cohesion Biosciences
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LARS2 miRNA 3'UTR clone - MiUTR1H-05579 from Creative biogene
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