BDNF

Gene Symbol	BDNF
Entrez Gene	627
Alt Symbol	ANON2, BULN2
Species	Human
Gene Type	protein-coding
Description	brain-derived neurotrophic factor
Other Description	abrineurin|neurotrophin
Swissprots	D3DQZ2 A7LA92 Q598Q1 A7LA85 Q9BYY7 Q6YNR3 Q9UC24 P23560 Q6YNR2 Q6DN19
Accessions	AAA51820 AAA96140 AAG47514 AAO15434 EAW68274 EAW68275 EAW68276 EAW68277 EAW68278 EAW68279 P23560 AB038670 BAB55545 AB038671 BAB55546 AB038672 BAB55547 AB038673 BAB55548 AB038674 BAB55549 AF400438 AAK92487 AK289763 BAF82452 AK289853 BAF82542 AY054392 AAL23557 AY054393 AAL23558 AY054394 AAL23559 AY054395 AAL23560 AY054396 AAL23561 AY054397 AAL23562 AY054398 AAL23563 AY054399 AAL23564 AY054400 AAL23565 AY054406 AAL23571 AY442188 AAR14686 AY656701 AAT74399 BC029795 AAH29795 CX751420 DQ250642 ABB51155 DQ890811 ABM81737 DQ893966 ABM84892 EF674517 ABS29021 EF674518 ABS29022 EF674519 ABS29023 EF674520 ABS29024 EF674521 ABS29025 EF689009 ABS32249 EF689010 ABS32250 EF689011 ABS32251 EF689012 ABS32252 EF689013 ABS32253 EF689014 ABS32254 EF689015 ABS32255 EF689016 ABS32256 EF689017 ABS32257 EF689018 ABS32258 EF689019 ABS32259 EF689020 ABS32260 EF689021 ABS32261 KC855559 AGR50950 KP229412 AKB90516 M61176 AAA69805 X60201 CAA42761 X91251 CAA62632 XM_011520280 XP_011518582 NM_001143805 NP_001137277 NM_001143806 NP_001137278 NM_001143807 NP_001137279 NM_001143808 NP_001137280 NM_001143809 NP_001137281 NM_001143810 NP_001137282 NM_001143811 NP_001137283 NM_001143812 NP_001137284 NM_001143813 NP_001137285 NM_001143814 NP_001137286 NM_001143816 NP_001137288 NM_001709 NP_001700 NM_170731 NP_733927 NM_170732 NP_733928 NM_170733 NP_733929 NM_170734 NP_733930 NM_170735 NP_733931 NM_001143815
Function	During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. {ECO:0000269|PubMed:12553913}.
Subcellular Location	Secreted.
Tissue Specificity	Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta. {ECO:0000269|PubMed:17629449}.
Top Pathways	Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway, Cocaine addiction, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BDNF Human ELISA Kit - ab99978 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 80 pg/ml Range 0.066 ng/ml - 16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F2402 from LifeSpan Bioscience Category ELISA Kit Prices $420.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 0.066-16 ng/ml

Mouse BDNF ELISA Kit (Sandwich ELISA) - LS-F2404 from LifeSpan Bioscience Category ELISA Kit Prices $420.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 0.066-16 ng/ml

Rat BDNF ELISA Kit (Sandwich ELISA) - LS-F2403 from LifeSpan Bioscience Category ELISA Kit Prices $420.00 Sizes 1 plate Sensitivity 2 pg/ml Range 0.066-16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F3960 from LifeSpan Bioscience Category ELISA Kit Prices $510.00 Sizes 1 plate Sensitivity 0.068 ng/ml Range 0.066-16 ng/ml

Rabbit BDNF ELISA Kit (Sandwich ELISA) - LS-F6495 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.066-16 ng/ml

Mouse BDNF ELISA Kit (Sandwich ELISA) - LS-F3964 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.066-16 ng/ml

Rat BDNF ELISA Kit (Sandwich ELISA) - LS-F3963 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 7.8 pg/ml Range 0.066-16 ng/ml

Dog BDNF ELISA Kit (Sandwich ELISA) - LS-F6222 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 0.066-16 ng/ml

Guinea pig BDNF ELISA Kit (Sandwich ELISA) - LS-F6223 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.066-16 ng/ml

Pig BDNF ELISA Kit (Sandwich ELISA) - LS-F6224 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.066-16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F35 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.066 ng/ml Range 0.066-16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F678 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.066-16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F9976 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 0.3125 ng/ml Range 0.066-16 ng/ml

Human BDNF ELISA Kit (Sandwich ELISA) - LS-F10928 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 0.066-16 ng/ml

Rat BDNF ELISA Kit (Sandwich ELISA) - LS-F10929 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 78 Range 0.066-16 ng/ml

Pig BDNF ELISA Kit (Sandwich ELISA) - LS-F10927 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.156 Range 0.066-16 ng/ml

Human BDNF ELISA Kit - RAB0026 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human BDNF Biotinylated Fluorokine Flow Cytometry Kit - NFBDNF from R&D Systems Prices $405.00 Sizes 1 kit

Human Free BDNF Quantikine ELISA Kit - DBD00 from R&D Systems Category ELISA Kit Prices $519.00, $2,491.00, $16,868.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 20 pg/mL Range 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Heparin Plasma, Citrate Plasma)

Human BDNF Quantikine PharmPak (50 Plates) - PDBD00 from R&D Systems Category ELISA Kit Sensitivity 20 pg/mL Range 62.5 - 4,000 pg/mL (Serum, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Platelet-poor Heparin Plasma)

Human BDNF Quantikine SixPak (6 Plates) - SBD00 from R&D Systems Category ELISA Kit Sensitivity 20 pg/mL Range 62.5 - 4,000 pg/mL (Serum, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Platelet-poor Heparin Plasma)

Human/Mouse BDNF DuoSet ELISA - DY248 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 23.40 - 1,500 pg/mL

Human Pro-BDNF DuoSet ELISA - DY3175 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 78.10 - 5,000 pg/mL

BDNF ELISA Kit (Human) : 96 Wells (OKAG00197) - OKAG00197 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 47 pg/mL Range 47-1500 pg/mL

Search more