| Gene Symbol | IL1B |
|---|---|
| Entrez Gene | 100860816 |
| Alt Symbol | - |
| Species | Goat |
| Gene Type | protein-coding |
| Description | interleukin 1, beta |
| Other Description | IL-1 beta|Interleukin-1 beta|interleukin-1 beta|precursor interleukin-1beta |
| Swissprots | P79162 |
| Accessions | P79162 D63351 BAA09675 XM_005686747 XP_005686804 |
| Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| Top Pathways | Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Cytokine-cytokine receptor interaction, Amoebiasis, Apoptosis |
Recombinant Goat Interleukin-1 beta(IL1B) - CSB-YP011614GO CSB-EP011614GO CSB-BP011614GO CSB-MP011614GO from Cusabio
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Interleukin-1 beta (IL1B), Recombinant Protein - MBS949816 from MyBioSource
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