Gene Symbol | PPIE |
---|---|
Entrez Gene | 10450 |
Alt Symbol | CYP-33, CYP33 |
Species | Human |
Gene Type | protein-coding |
Description | peptidylprolyl isomerase E (cyclophilin E) |
Other Description | PPIase E|cyclophilin-33|peptidyl-prolyl cis-trans isomerase E|rotamase E |
Swissprots | B2R971 O43634 Q5TGA3 Q32Q72 O43635 Q5TGA0 Q5TGA2 Q9UIZ5 Q9UNP9 Q3S611 |
Accessions | EAX07255 EAX07256 Q9UNP9 AF042385 AAC00006 AF042386 AAC00007 AF104012 AAD19906 AF104013 AAD19907 AI079772 AK094660 BAG52903 AK130628 AK293094 BAF85783 AK304694 BAG65464 AK313666 BAG36418 AL833576 BC004898 AAH04898 BC008451 AAH08451 BC107736 AAI07737 BU160972 BU179717 BU196539 BU689929 CA445146 CK300365 DA079924 DQ160195 AAZ93379 HQ447404 ADQ31890 XM_006710289 XP_006710352 XM_006710290 XP_006710353 XM_006710291 XP_006710354 XM_006710292 XP_006710355 XM_011540501 XP_011538803 XR_946519 XR_946520 XR_946521 NM_001195007 NP_001181936 NM_006112 NP_006103 NM_203456 NP_982281 NR_036543 NR_036544 NM_203457 |
Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Combines RNA-binding and PPIase activities. May be involved in muscle- and brain-specific processes. May be involved in pre-mRNA splicing. |
Subcellular Location | Nucleus. |
Tissue Specificity | Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Top Pathways | Spliceosome |