Gene Symbol |
ptf1a
|
Entrez Gene |
368662
|
Alt Symbol |
PTF1, si:zc142h2.2, zgc:112216
|
Species |
Zebrafish
|
Gene Type |
protein-coding
|
Description |
pancreas specific transcription factor, 1a
|
Other Description |
Ptfa|bHLH transcription factor p48|pancreas transcription factor 1 subunit alpha|pancreas-specific transcription factor 1a
|
Swissprots |
Q7ZSX3
|
Accessions |
Q7ZSX3 AY245546 AAO92259 BC093269 AAH93269 NM_207641 NP_997524
|
Function |
Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Required for exocrine pancreatic development. Plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates. {ECO:0000269|PubMed:15183727}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|