Gene Symbol | PPP1R42 |
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Entrez Gene | 286187 |
Alt Symbol | LRRC67, TLLR, dtr |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory subunit 42 |
Other Description | leucine rich repeat containing 67|leucine-rich repeat-containing protein 67|protein phosphatase 1 regulatory subunit 42|testis leucine-rich repeat |
Swissprots | Q7Z4L9 |
Accessions | EAW86927 Q7Z4L9 BC055413 AAH55413 NM_001013626 NP_001013648 |
Function | Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Colocalizes with alpha tubulin to the manchette of developing spermatids. Detected to nuclear rim in pachytene spermatocytes. Detected at nuclear surface, opposite the acrosome in elongating spermatids. Detected at the microtubule- organizing center (MTOC). Localized to the centrosomal region of late-stage spermatids (By similarity). {ECO:0000250}. |
LRRC67 CRISPR/Cas9 KO Plasmid (h) - sc-418388 from Santa Cruz Biotechnology
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LRRC67 HDR Plasmid (h) - sc-418388-HDR from Santa Cruz Biotechnology
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LRRC67 Double Nickase Plasmid (h) - sc-418388-NIC from Santa Cruz Biotechnology
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LRRC67 Double Nickase Plasmid (h2) - sc-418388-NIC-2 from Santa Cruz Biotechnology
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LRRC67 CRISPR Activation Plasmid (h) - sc-418388-ACT from Santa Cruz Biotechnology
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LRRC67 CRISPR Activation Plasmid (h2) - sc-418388-ACT-2 from Santa Cruz Biotechnology
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LRRC67 Lentiviral Activation Particles (h) - sc-418388-LAC from Santa Cruz Biotechnology
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LRRC67 Lentiviral Activation Particles (h2) - sc-418388-LAC-2 from Santa Cruz Biotechnology
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LRRC67 siRNA (h) - sc-77829 from Santa Cruz Biotechnology
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LRRC67 shRNA Plasmid (h) - sc-77829-SH from Santa Cruz Biotechnology
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LRRC67 shRNA (h) Lentiviral Particles - sc-77829-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12760 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12760 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01625 from Sigma-Aldrich
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PPP1R42 siRNA (Human) - CRJ7156 from Cohesion Biosciences
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shRNA set against Human LOC286187(NM_001013626.2) - SHH153911 from Creative biogene
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Human PPP1R42 siRNA - orb277657 from Biorbyt
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PPP1R42 shRNA Plasmid (Human) - CHJ7156 from Cohesion Biosciences
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PPP1R42 miRNA 3'UTR clone - MiUTR1H-05773 from Creative biogene
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