Gene Symbol |
IL12B
|
Entrez Gene |
768273
|
Alt Symbol |
IL-12.p40
|
Species |
Cat
|
Gene Type |
protein-coding
|
Description |
interleukin 12B
|
Other Description |
CLMF p40|IL-12 subunit p40|IL-12B|cytotoxic lymphocyte maturation factor 40 kDa subunit|interleukin 12 p40 subunit|interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)|interleukin-12 beta chain|interleukin-12 p40 chain|interleukin-12 subunit beta
|
Swissprots |
O02744 O46671
|
Accessions |
O02744 AF054607 AAC15980 U83184 AAB93835 Y07762 CAA69068 NM_001077413 NP_001070881
|
Function |
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. {ECO:0000250}.
|
Subcellular Location |
Secreted.
|
Top Pathways |
Amoebiasis, Toll-like receptor signaling pathway, Proteoglycans in cancer, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)
|