Gene Symbol | NPPA |
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Entrez Gene | 608289 |
Alt Symbol | ANF, ANP |
Species | Dog |
Gene Type | protein-coding |
Description | natriuretic peptide A |
Other Description | atrial natriuretic factor|atrial natriuretic peptide|natriuretic peptide precursor A|natriuretic peptides A|prepronatriodilatin |
Swissprots | P07499 |
Accessions | P07499 XM_845264 XP_850357 |
Function | Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Anti-ANP antibody - N-terminal - ab91250 from Abcam
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Anti-proANP antibody - ab14349 from Abcam
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Anti-proANP antibody [A137-M14-19-F9] - ab14482 from Abcam
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Monoclonal Antibody to Atrial Natriuretic Peptide (ANP) - MAA225Ca21 from Cloud-clone
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Polyclonal Antibody to Atrial Natriuretic Peptide (ANP) - PAA225Ca01 from Cloud-clone
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