Gene Symbol |
GSTT2B
|
Entrez Gene |
653689
|
Alt Symbol |
GSTT2P
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
glutathione S-transferase theta 2B (gene/pseudogene)
|
Other Description |
GST class-theta-2|glutathione S-transferase theta 2|glutathione S-transferase theta-2|glutathione S-transferase theta-2B
|
Swissprots |
P0CG30
|
Accessions |
AEW26630 AEW26631 AEW26632 P0CG30 BC071700 AAH71700 BC146936 AAI46937 XM_005261715 XP_005261772 XM_011546907 XP_011545209 NM_001080843 NP_001074312
|
Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. {ECO:0000269|PubMed:8761485}.
|
Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|