CCKBR

Gene Symbol CCKBR
Entrez Gene 281665
Alt Symbol -
Species Bovine
Gene Type protein-coding
Description cholecystokinin B receptor
Other Description CCK-B receptor|CCK-BR|CCK2 receptor|CCK2-R|cholecystokinin-2 receptor|gastrin/cholecystokinin type B receptor
Swissprots Q2KI20 P79266
Accessions DAA22129 P79266 BC112800 AAI12801 S83090 AAB46896 XM_010812587 XP_010810889 NM_174262 NP_776687
Function Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction

Anti-CCKBR antibody - ab77077 from Abcam

Prices $379.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab77077 (4µg/ml) staining of paraffin embedded Human Pancreas tissue. Steamed antigen retrieval carried using Tris/EDTA buffer pH 9 followed by HRP-staining.

Anti-CCKBR antibody - ab14440 from Abcam

Prices $379.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CCKBR antibody - ab14439 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CCKBR antibody - Extracellular domain - ab140774 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin embedded Human stomach tissue labelling CCKBR with ab140774 at 11 µg/ml.
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