Gene Symbol |
CCKBR
|
Entrez Gene |
281665
|
Alt Symbol |
-
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
cholecystokinin B receptor
|
Other Description |
CCK-B receptor|CCK-BR|CCK2 receptor|CCK2-R|cholecystokinin-2 receptor|gastrin/cholecystokinin type B receptor
|
Swissprots |
Q2KI20 P79266
|
Accessions |
DAA22129 P79266 BC112800 AAI12801 S83090 AAB46896 XM_010812587 XP_010810889 NM_174262 NP_776687
|
Function |
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction
|