Gene Symbol |
TMF1
|
Entrez Gene |
7110
|
Alt Symbol |
ARA160, TMF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
TATA element modulatory factor 1
|
Other Description |
TATA element modulatory factor|androgen receptor coactivator 160 kDa protein|androgen receptor-associated protein of 160 kDa
|
Swissprots |
Q17R87 Q59GK0 P82094 B7ZLJ2
|
Accessions |
EAW65468 EAW65469 P82094 AB209109 BAD92346 AK021741 AK096365 AK299020 BAG61099 AK312697 AL040699 BC008454 BC033771 AAH33771 BC117418 AAI17419 BC126123 AAI26124 BC143840 AAI43841 BU689613 L01042 AAD54608 XM_011534056 XP_011532358 NM_007114 NP_009045
|
Function |
Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). {ECO:0000269|PubMed:10428808, ECO:0000269|PubMed:1409643, ECO:0000269|PubMed:15467733, ECO:0000269|PubMed:17698061}.
|
Subcellular Location |
Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae.
|