| Gene Symbol |
TNFAIP8L2
|
| Entrez Gene |
79626
|
| Alt Symbol |
TIPE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tumor necrosis factor, alpha-induced protein 8-like 2
|
| Other Description |
TNF alpha-induced protein 8-like protein 2|TNFAIP8-like protein 2|inflammation factor 20|inflammation factor protein 20|tumor necrosis factor alpha-induced protein 8-like protein 2|tumor necrosis factor, alpha-induced protein 8-like protein 2
|
| Swissprots |
Q9H5G2 Q6I9Y0 Q6P589 Q9H2H7
|
| Accessions |
CAI48009 CCQ77682 EAW53468 Q6P589 AF271774 AAG44785 AF548003 AAQ12262 AK027120 BAB15664 AK225472 AL833373 CAI46145 BC012013 BC063014 AAH63014 BI833715 CR457375 CAG33656 NM_024575 NP_078851
|
| Function |
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity). {ECO:0000250}.
|
![Western Blot: TNFAIP8L2 Overexpression Lysate (Adult Normal) [NBL1-17140] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TNFAIP8L2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3911_TNFAIP8L2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17140-img0002.jpg)