Gene Symbol |
GMEB2
|
Entrez Gene |
26205
|
Alt Symbol |
P79PIF, PIF79
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
glucocorticoid modulatory element binding protein 2
|
Other Description |
DNA-binding protein p79PIF|GMEB-2|PIF p79|glucocorticoid modulatory element-binding protein 2|parvovirus initiation factor p79|parvovirus initiation factor, p79
|
Swissprots |
Q9H4X8 Q5TDS0 Q9H431 Q9H4X7 Q9ULF1 Q9UKD1 E1P5J3 Q9UF78
|
Accessions |
EAW75252 EAW75253 EAW75254 Q9UKD1 AB033095 BAA86583 AF173867 AAD51351 AK298927 BAG61032 AL117510 CAH56403 AL133646 CAB63765 BC036305 AAH36305 BQ954281 DB474085 EU446699 ABZ92228 XM_005260202 XP_005260259 XM_006723776 XP_006723839 XM_011528779 XP_011527081 NM_012384 NP_036516
|
Function |
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
|
Subcellular Location |
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
|
Tissue Specificity |
Expressed in peripheral blood lymphocytes and fetal liver. Expressed preferentially in reproductive and/or developmentally important cells, such as testis, placenta, bone marrow and fetal tissues.
|