Gene Symbol | Arl6ip5 |
---|---|
Entrez Gene | 66028 |
Alt Symbol | Gtrap3-18 |
Species | Rat |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 6 interacting protein 5 |
Other Description | ADP-ribosylation factor-like protein 6-interacting protein 5|ADP-ribosylation-like factor 6 interacting protein 5|ARL-6-interacting protein 5|PRA1 family protein 3|aip-5|glutamate transporter EAAC1 interacting protein|glutamate transporter EAAC1-interacting protein|prenylated Rab acceptor protein 2|protein JWa |
Swissprots | Q9ES40 Q9JKD1 |
Accessions | EDL91425 EDL91426 Q9ES40 AF240182 AAG28598 BC061548 AAH61548 FQ213351 FQ213919 FQ216190 FQ216551 FQ225681 FQ228780 FQ232358 NM_023972 NP_076462 |
Function | Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. {ECO:0000269|PubMed:11242046, ECO:0000269|Ref.5}. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules. |
Tissue Specificity | Ubiquitous. Most abundant in heart and brain. {ECO:0000269|PubMed:11096102}. |