ZFYVE27
| Gene Symbol | ZFYVE27 |
|---|---|
| Entrez Gene | 118813 |
| Alt Symbol | PROTRUDIN, SPG33 |
| Species | Human |
| Gene Type | protein-coding |
| Description | zinc finger, FYVE domain containing 27 |
| Other Description | protrudin |
| Swissprots | J3KP98 Q5T4F1 G8JLF0 Q96M08 G8JLC3 Q5T4F3 B7Z626 B7Z3S0 Q8NCA0 Q5T4F4 Q5T4F2 Q8N1K0 Q8NDE4 B7Z404 Q8N6D6 |
| Accessions | EAW49895 EAW49896 EAW49897 EAW49898 EAW49899 EAW49900 EAW49901 EAW49902 Q5T4F4 AK057481 BAB71506 AK074876 BAC11260 AK097945 BAC05200 AK296295 BAH12306 AK296588 BAH12390 AK299735 BAH13112 AK300438 BAH13285 AL561314 AL834235 CAD38913 BC030621 AAH30621 BF063694 BF508037 BI758753 BM544601 BU838354 BX647836 CB150532 DC302372 XM_005269502 XP_005269559 XM_005269503 XP_005269560 XM_005269504 XP_005269561 XM_005269505 XP_005269562 XM_005269506 XP_005269563 XM_005269508 XP_005269565 XM_005269509 XP_005269566 XM_005269510 XP_005269567 XM_005269511 XP_005269568 XM_011539252 XP_011537554 XM_011539253 XP_011537555 XM_011539254 XP_011537556 XM_011539255 XP_011537557 XM_011539256 XP_011537558 XR_945594 XR_945595 XR_945596 XR_945597 NM_001002261 NP_001002261 NM_001002262 NP_001002262 NM_001174119 NP_001167590 NM_001174120 NP_001167591 NM_001174121 NP_001167592 NM_001174122 NP_001167593 NM_144588 NP_653189 |
| Function | Functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. Involved in nerve growth factor-induced neurite formation. May have a more general role in cell projections formation. {ECO:0000269|PubMed:17082457, ECO:0000269|PubMed:19289470}. |
| Subcellular Location | Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Localizes at both dendrites and axons. {ECO:0000250}. |
ZFYVE27 CRISPR/Cas9 KO Plasmid (h) - sc-407267 from Santa Cruz Biotechnology
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ZFYVE27 HDR Plasmid (h) - sc-407267-HDR from Santa Cruz Biotechnology
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ZFYVE27 Double Nickase Plasmid (h) - sc-407267-NIC from Santa Cruz Biotechnology
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ZFYVE27 Double Nickase Plasmid (h2) - sc-407267-NIC-2 from Santa Cruz Biotechnology
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ZFYVE27 CRISPR Activation Plasmid (h) - sc-407267-ACT from Santa Cruz Biotechnology
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ZFYVE27 CRISPR Activation Plasmid (h2) - sc-407267-ACT-2 from Santa Cruz Biotechnology
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ZFYVE27 Lentiviral Activation Particles (h) - sc-407267-LAC from Santa Cruz Biotechnology
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ZFYVE27 Lentiviral Activation Particles (h2) - sc-407267-LAC-2 from Santa Cruz Biotechnology
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ZFYVE27 siRNA (h) - sc-90825 from Santa Cruz Biotechnology
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ZFYVE27 shRNA Plasmid (h) - sc-90825-SH from Santa Cruz Biotechnology
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ZFYVE27 shRNA (h) Lentiviral Particles - sc-90825-V from Santa Cruz Biotechnology
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ZFYVE27 RNAi - H00118813-R02 from Novus Biologicals
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ZFYVE27 RNAi - H00118813-R01 from Novus Biologicals
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MISSION® esiRNA - EHU077281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23208 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23208 from Sigma-Aldrich
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ZFYVE27 siRNA (Human) - CRJ4598 from Cohesion Biosciences
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ZFYVE27 RNAi - H00118813-R03 from Novus Biologicals
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ZFYVE27 - MBS8224858 from MyBioSource
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shRNA set against Human ZFYVE27 (NM_144588.6) - SHH452516 from Creative biogene
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Human ZFYVE27 siRNA - orb275099 from Biorbyt
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ZFYVE27 shRNA Plasmid (Human) - CHJ4598 from Cohesion Biosciences
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ZFYVE27 miRNA 3'UTR clone - MiUTR3H-11105 from Creative biogene
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ZFYVE27 miRNA 3'UTR clone - MiUTR3H-11106 from Creative biogene
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ZFYVE27 miRNA 3'UTR clone - MiUTR3H-11107 from Creative biogene
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