Gene Symbol | ABCA5 |
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Entrez Gene | 23461 |
Alt Symbol | ABC13, EST90625 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 5 |
Other Description | ATP-binding cassette A5|ATP-binding cassette sub-family A member 5 |
Swissprots | Q9NY14 Q8IVJ2 Q96LJ1 Q96PZ9 Q8WWZ7 Q96MS4 |
Accessions | EAW89080 EAW89081 EAW89082 EAW89083 Q8WWZ7 AB067475 BAB67781 AJ275973 CAB93535 AJ512612 CAD54757 AK056533 BAB71208 AK058170 BAB71700 AK094416 AK096664 AK122803 AK292592 BAF85281 AY028897 AAK30022 BC029426 AAH29426 BC054480 BC070126 BC146819 BC156256 AAI56257 BF448717 BX640746 CAE45856 BX647447 BX648540 DB096625 NM_018672 NP_061142 NM_172232 NP_758424 |
Function | May play a role in the processing of autolysosomes. {ECO:0000250}. |
Subcellular Location | Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. {ECO:0000269|PubMed:12504089, ECO:0000269|Ref.1}. |
Top Pathways | ABC transporters |
ABCA5 CRISPR/Cas9 KO Plasmid (h) - sc-410568 from Santa Cruz Biotechnology
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ABCA5 HDR Plasmid (h) - sc-410568-HDR from Santa Cruz Biotechnology
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ABCA5 Double Nickase Plasmid (h) - sc-410568-NIC from Santa Cruz Biotechnology
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ABCA5 Double Nickase Plasmid (h2) - sc-410568-NIC-2 from Santa Cruz Biotechnology
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ABCA5 CRISPR Activation Plasmid (h) - sc-410568-ACT from Santa Cruz Biotechnology
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ABCA5 CRISPR Activation Plasmid (h2) - sc-410568-ACT-2 from Santa Cruz Biotechnology
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ABCA5 Lentiviral Activation Particles (h) - sc-410568-LAC from Santa Cruz Biotechnology
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ABCA5 Lentiviral Activation Particles (h2) - sc-410568-LAC-2 from Santa Cruz Biotechnology
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ABCA5 siRNA (h) - sc-94206 from Santa Cruz Biotechnology
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ABCA5 shRNA Plasmid (h) - sc-94206-SH from Santa Cruz Biotechnology
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ABCA5 shRNA (h) Lentiviral Particles - sc-94206-V from Santa Cruz Biotechnology
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ABCA5 RNAi - H00023461-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2622 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2622 from Sigma-Aldrich
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ABCA5 siRNA (Human) - CRH8283 from Cohesion Biosciences
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ABCA5 RNAi - H00023461-R01 from Novus Biologicals
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ABCA5 - MBS829162 from MyBioSource
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shRNA set against Human ABCA5 (NM_018672.3) - SHH228874 from Creative biogene
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shRNA set against Human ABCA5(NM_018672.3) - SHG022793 from Creative biogene
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ABCA5 shRNA Plasmid (Human) - CHH8283 from Cohesion Biosciences
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ABCA5 miRNA 3'UTR clone - MiUTR1H-00022 from Creative biogene
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