| Gene Symbol |
TMEM74
|
| Entrez Gene |
157753
|
| Alt Symbol |
NET36
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 74
|
| Other Description |
-
|
| Swissprots |
Q96NL1
|
| Accessions |
EAW91921 EAW91922 Q96NL1 AK055230 BAB70881 BC030710 AAH30710 BC033057 HQ447393 ADQ31879 NM_153015 NP_694560
|
| Function |
Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction. {ECO:0000269|PubMed:18294959, ECO:0000269|PubMed:19029833}.
|
| Subcellular Location |
Lysosome membrane {ECO:0000269|PubMed:18294959}; Multi-pass membrane protein {ECO:0000269|PubMed:18294959}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:18294959}; Multi-pass membrane protein {ECO:0000269|PubMed:18294959}.
|
| Tissue Specificity |
Expressed in heart, lung, and placenta. {ECO:0000269|PubMed:18294959}.
|
