Fos

Gene Symbol Fos
Entrez Gene 100689418
Alt Symbol -
Species Hamster
Gene Type protein-coding
Description FBJ murine osteosarcoma viral oncogene homolog
Other Description Cellular oncogene fos|FBJ osteosarcoma oncogene|c-fos protooncogene protein|proto-oncogene c-Fos
Swissprots Q9Z2Q8
Accessions Q9Z2Q8 AF033012 AAC83461 NM_001246683 NP_001233612
Function Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta- mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity). {ECO:0000250}.
Top Pathways Choline metabolism in cancer, Oxytocin signaling pathway, cAMP signaling pathway, Toll-like receptor signaling pathway, Pertussis

Proto-oncogene c-Fos (FOS), Recombinant Protein - MBS1370888 from MyBioSource

Category Protein
Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00, $2,300.00, $2,300.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Hamster

Proto-oncogene c-Fos (FOS), Recombinant Protein - MBS1048238 from MyBioSource

Category Protein
Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00, $2,300.00, $2,300.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Hamster

Proto-oncogene c-Fos (FOS), Recombinant Protein - MBS1282815 from MyBioSource

Category Protein
Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00, $2,300.00, $2,300.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Hamster
Search more