GALNT12

Gene Symbol	GALNT12
Entrez Gene	79695
Alt Symbol	CRCS1, GalNAc-T12
Species	Human
Gene Type	protein-coding
Description	polypeptide N-acetylgalactosaminyltransferase 12
Other Description	UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)|colorectal cancer, susceptibility to 1|polypeptide GalNAc transferase 12|pp-GaNTase 12|protein-UDP acetylgalactosaminyltransferase 12
Swissprots	Q5TCF7 Q9H771 Q8IXK2 Q96CT9 Q8NG54
Accessions	CAG32962 EAW58897 Q8IXK2 AB040673 BAD93346 AB078146 BAC07181 AJ132365 CAC80100 AJ505963 CAD44541 AK024865 BAB15027 BC013945 AAH13945 BC148409 AAI48410 BC148739 AAI48740 CB243715 XM_006717287 XP_006717350 XM_011519018 XP_011517320 XM_011519019 XP_011517321 XM_011519020 XP_011517322 NM_024642 NP_078918
Function	Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc- Muc5AC glycopeptide, but no detectable activity to mono-GalNAc- glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed at different levels of expression. Highly expressed in digestive organs such as small intestine, stomach, pancreas and colon. Expressed at intermediate level in testis, thyroid gland and spleen. Weakly expressed in whole brain, cerebral cortex, cerebellum, fetal brain, bone marrow, thymus, leukocytes, heart, skeletal muscle, liver, lung, esophagus, kidney, adrenal gland, mammary gland, uterus, placenta, ovary and prostate. {ECO:0000269|PubMed:12135769}.
Top Pathways	Mucin type O-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GalNAc-T12 (A-14) - sc-68501 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GalNAc-T12 (E-14) - sc-68502 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-GALNT12 antibody - ab201196 from Abcam Prices $359.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GALNT12 antibody - ab101358 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-GALNT12 Antibody - LS-C307645 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-GALNT12 Antibody - LS-C310438 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

GALNT12 Antibody - H00079695-D02P from Novus Biologicals Prices $399.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

GALNT12 Antibody - NBP2-14035 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GALNT12 Antibody - NBP2-16594 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GALNT12 Antibody - H00079695-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

GALNT12 Antibody - H00079695-B02 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

GALNT12 Antibody - H00079695-D01P from Novus Biologicals Prices $399.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody - bs-13272R from Bioss Prices $245.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13272R-A350 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13272R-A488 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13272R-A555 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13272R-A647 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, Cy3 Conjugated - bs-13272R-Cy3 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, Cy5 Conjugated - bs-13272R-Cy5 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, Cy5.5 Conjugated - bs-13272R-Cy5.5 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, Cy7 Conjugated - bs-13272R-Cy7 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, FITC Conjugated - bs-13272R-FITC from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, Biotin Conjugated - bs-13272R-Biotin from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-GALNT12/GalNAc-T12 Polyclonal Antibody, HRP Conjugated - bs-13272R-HRP from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-GALNT12 antibody produced in rabbit - HPA048292 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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