SPINK1

Gene Symbol SPINK1
Entrez Gene 6690
Alt Symbol PCTT, PSTI, Spink3, TATI, TCP
Species Human
Gene Type protein-coding
Description serine peptidase inhibitor, Kazal type 1
Other Description pancreatic secretory trypsin inhibitor|serine protease inhibitor, Kazal type 1|tumor-associated trypsin inhibitor
Swissprots P00995
Accessions AAA36522 AAG00531 ABH06583 ABH06584 EAW61817 P00995 AI990990 BC025790 AAH25790 BU074107 CB159576 DQ893613 ABM84539 DQ896842 ABM87841 M11949 AAA36521 Y00705 CAA68697 NM_003122 NP_003113
Function This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.
Subcellular Location Secreted.

TATI (E-2) - sc-374409 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TATI (E-2): sc-374409. Western blot analysis of human recombinant SPINK1/TATI.

TATI (FL-79) - sc-98726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TATI (FL-79): sc-98726. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells and cytoplasmic and membrane staining of Islets of Langerhans.

TATI (G-13) - sc-46652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SPINK1 antibody - ab58227 from Abcam

Prices $382.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
SPINK1 antibody (ab58227) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human pancreas.

Anti-SPINK1 antibody - ab98183 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of SPINK1 staining in humn pancreas formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab98183, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SPINK1 antibody - ab183769 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of MCF-7 cells (fixed in ice-cold methanol for 5 mins) labeling SPINK1 with ab183769 at 1/500 dilution (green). Blue: Hoechst 33342 staining.

Anti-SPINK1 antibody [4D4] - ab117541 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D4
Human Pancreas, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117541 at 5µg/ml.

Anti-SPINK1 antibody [BA1] - ab183307 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BA1
Immunofluorescent analysis of PANC1 cells, labeling SPINK1 with ab183307.

Anti-SPINK1 antibody [EPR12696(2)] - ab183034 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12696(2)
Immunohistochemical analysis of Paraffin-embedded Human pancreas tissue labeling SPINK1 with ab183034 at 1/4000 dilution followed by pre-diluted HRP-conjugated secondary antibody and counter-stained with Hematoxylin.

Anti-SPINK1 antibody [SP166] - ab183347 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP166
Anti-SPINK1 antibody [SP166] (ab183347) at 1/100 dilution + Human pancreas lysate

Anti-TATI / SPINK1 Antibody (aa1-79) - LS-C311903 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-SPINK1 antibody used in ICC/IF.

Anti-SPINK1 Antibody (N-Terminus) - LS-C80077 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.

Anti-SPINK1 Antibody - LS-C192369 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of SPINK1 pAb in extracts from GST-SPINK1 recombinant protein.

Anti-SPINK1 Antibody (aa26-78) - LS-C296388 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TATI / SPINK1.

Anti-SPINK1 Antibody - LS-C335125 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SPINK1 antibody.

Anti-SPINK1 Antibody (clone 4D4) IHC-plus™ - LS-B5538 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D4
Anti-SPINK1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5538 concentration 5 ug/ml.

Anti-SPINK1 Antibody (clone SP166) - LS-C210396 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Rabbit
Clonality Monoclonal
Clone SP166
Immunohistochemistry of Human Prostate Adenocarcinoma stained with anti-Spink1 antibody

SPINK1 Antibody (4D4) - H00006690-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D4
Western Blot: SPINK1 Antibody (4D4) [H00006690-M01] - detection against Immunogen (31.9 KDa).Antibody reactive against recombinant protein.

SPINK1 Antibody (839305) [Unconjugated] - MAB7496 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 839305
Simple Western lane view shows lysates of human pancreas tissue, loaded at 0.5 mg/mL. A specific band was detected for SPINK1 at approximately 6 kDa (as indicated) using 100 µg/mL of Mouse Anti-Human SPINK1 Monoclonal Antibody (Catalog # MAB7496). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody.

SPINK1 Antibody - NBP2-29620 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SPINK1 Antibody [NBP2-29620] - Western blot analysis of SPINK1 in PANC-1 cell lysate in the A) absence and B) presence of immunizing peptide.

SPINK1 Antibody [Unconjugated] - AF7496 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human pancreas tissue. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human SPINK1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7496) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for SPINK1 at approximately 6 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

SPINK1 Antibody - 34750002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SPINK1 Antibody - H00006690-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SPINK1 Antibody - NBP1-87314 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPINK1 Antibody (4D4) - H00006690-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 4D4
Western Blot: SPINK1 Antibody (4D4) [H00006690-M01A] - SPINK1 monoclonal antibody (M01), clone 4D4. Western Blot analysis of SPINK1 expression in human pancreas.
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