Gene Symbol | EIF5 |
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Entrez Gene | 1983 |
Alt Symbol | EIF-5, EIF-5A |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 5 |
Other Description | - |
Swissprots | Q9UG48 Q9H5N2 Q53XB3 P55010 |
Accessions | EAW81808 EAW81809 EAW81810 EAW81811 P55010 AK026933 BAB15593 AK027240 AK074470 AK293712 BAG57144 AL080102 CAB45711 BC000106 BC007728 AAH07728 BC015630 AAH15630 BC032866 AAH32866 BC041083 BC107884 AAI07885 BF979642 BI459720 BX429104 BX537367 CAD97610 CR456712 CAG32993 CR627002 DB458085 DQ893482 ABM84408 EU832284 ACE87541 EU832369 ACE86854 HQ448292 ADQ32772 U49436 AAC50572 NM_001969 NP_001960 NM_183004 NP_892116 |
Function | Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). |
Top Pathways | RNA transport |
eIF5 CRISPR/Cas9 KO Plasmid (h) - sc-402133 from Santa Cruz Biotechnology
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eIF5 HDR Plasmid (h) - sc-402133-HDR from Santa Cruz Biotechnology
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eIF5 Double Nickase Plasmid (h) - sc-402133-NIC from Santa Cruz Biotechnology
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eIF5 Double Nickase Plasmid (h2) - sc-402133-NIC-2 from Santa Cruz Biotechnology
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eIF5 CRISPR Activation Plasmid (h) - sc-402133-ACT from Santa Cruz Biotechnology
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eIF5 CRISPR Activation Plasmid (h2) - sc-402133-ACT-2 from Santa Cruz Biotechnology
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eIF5 Lentiviral Activation Particles (h) - sc-402133-LAC from Santa Cruz Biotechnology
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eIF5 Lentiviral Activation Particles (h2) - sc-402133-LAC-2 from Santa Cruz Biotechnology
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eIF5 siRNA (h) - sc-35288 from Santa Cruz Biotechnology
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eIF5 shRNA Plasmid (h) - sc-35288-SH from Santa Cruz Biotechnology
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eIF5 shRNA (h) Lentiviral Particles - sc-35288-V from Santa Cruz Biotechnology
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EIF5 RNAi - H00001983-R04 from Novus Biologicals
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MISSION® esiRNA - EHU091491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7787 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7787 from Sigma-Aldrich
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EIF5 siRNA (Human) - CRH1372 from Cohesion Biosciences
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EIF5 RNAi - H00001983-R03 from Novus Biologicals
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EIF5 - MBS8200910 from MyBioSource
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shRNA set against Human EIF5 (NM_183004.4) - SHH284777 from Creative biogene
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EIF5 shRNA Plasmid (Human) - CHH1372 from Cohesion Biosciences
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EIF5 miRNA 3'UTR clone - MiUTR4H-TG11128 from Creative biogene
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