Gene Symbol |
SLC25A23
|
Entrez Gene |
79085
|
Alt Symbol |
APC2, MCSC2, SCaMC-3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
|
Other Description |
calcium-binding mitochondrial carrier protein SCaMC-3|mitochondrial ATP-Mg/Pi carrier protein 2|mitochondrial Ca(2+)-dependent solute carrier protein 2|mitochondrial Ca2+-dependent solute carrier protein 2|short calcium-binding mitochondrial carrier 3|small calcium-binding mitochondrial carrier protein 3|solute carrier family 25 member 23
|
Swissprots |
Q705K3 Q9BV35 Q96NQ4 Q86Y43 Q4LBC2 B4DGB6 Q8N2N4
|
Accessions |
EAW69087 EAW69088 EAW69089 Q9BV35 AJ512835 CAD55563 AJ619962 CAF04059 AJ619988 CAF04494 AJ879080 CAI51682 AJ879081 CAI51683 AJ879082 CAI51684 AJ879083 CAI51685 AK027562 AK054901 BAB70825 AK074579 BAC11071 AK294514 BAG57727 AK295484 BAG58407 AW379976 AY750170 AAU95077 BC001656 AAH01656 BG706035 HQ447924 ADQ32408 XM_011528274 XP_011526576 XM_011528275 XP_011526577 XM_011528276 XP_011526578 XM_011528277 XP_011526579 XM_011528278 XP_011526580 XM_011528279 XP_011526581 XM_011528280 XP_011526582 XM_011528281 XP_011526583 XM_011528282 XP_011526584 XM_011528283 XP_011526585 XM_011528284 XP_011526586 XM_011528285 XP_011526587 NM_024103 NP_077008
|
Function |
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. {ECO:0000269|PubMed:15123600}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}; Multi-pass membrane protein {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}.
|
Tissue Specificity |
Present in various cell lines (at protein level). Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}.
|