Gene Symbol | EML2 |
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Entrez Gene | 24139 |
Alt Symbol | ELP70, EMAP-2, EMAP2 |
Species | Human |
Gene Type | protein-coding |
Description | echinoderm microtubule associated protein like 2 |
Other Description | echinoderm MT-associated protein (EMAP)-like protein 70|echinoderm microtubule-associated protein-like 2|microtubule-associated protein like echinoderm EMAP |
Swissprots | Q9UG50 Q8N5A2 Q59EN8 K7ERL7 O95834 B7Z3I2 B7Z3Q9 |
Accessions | EAW57369 EAW57370 O95834 AB209773 BAD93010 AF103939 AAD19904 AK026616 AK225043 AK294668 BAH11841 AK295905 BAH12218 AK296258 BAH12295 AK302961 BAH13858 AK304299 BAH14154 AK308403 AK308580 AL096717 CAB46373 BC029304 BC032630 AAH32630 DC366776 XM_006723125 XP_006723188 XM_006723126 XP_006723189 XM_011526694 XP_011524996 XM_011526695 XP_011524997 XM_011526696 XP_011524998 XM_011526697 XP_011524999 XM_011526698 XP_011525000 XM_011526699 XP_011525001 XM_011526700 XP_011525002 XM_011526701 XP_011525003 XR_935785 XR_935786 XR_935787 NM_001193268 NP_001180197 NM_001193269 NP_001180198 NM_012155 NP_036287 NR_034098 |
Function | Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules. {ECO:0000269|PubMed:11694528}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11694528}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11694528}. Note=Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10521658}. |
EML2 CRISPR/Cas9 KO Plasmid (h) - sc-416235 from Santa Cruz Biotechnology
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EML2 HDR Plasmid (h) - sc-416235-HDR from Santa Cruz Biotechnology
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EML2 Double Nickase Plasmid (h) - sc-416235-NIC from Santa Cruz Biotechnology
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EML2 Double Nickase Plasmid (h2) - sc-416235-NIC-2 from Santa Cruz Biotechnology
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EML2 CRISPR Activation Plasmid (h) - sc-416235-ACT from Santa Cruz Biotechnology
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EML2 CRISPR Activation Plasmid (h2) - sc-416235-ACT-2 from Santa Cruz Biotechnology
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EML2 Lentiviral Activation Particles (h) - sc-416235-LAC from Santa Cruz Biotechnology
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EML2 Lentiviral Activation Particles (h2) - sc-416235-LAC-2 from Santa Cruz Biotechnology
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EML2 siRNA (h) - sc-97090 from Santa Cruz Biotechnology
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EML2 shRNA Plasmid (h) - sc-97090-SH from Santa Cruz Biotechnology
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EML2 shRNA (h) Lentiviral Particles - sc-97090-V from Santa Cruz Biotechnology
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EML2 RNAi - H00024139-R01 from Novus Biologicals
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MISSION® esiRNA - EHU012881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7845 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7845 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02654 from Sigma-Aldrich
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EML2 siRNA (Human) - CRH8468 from Cohesion Biosciences
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EML2 - MBS8201151 from MyBioSource
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shRNA set against Human EML2 (NM_012155.2) - SHH285517 from Creative biogene
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Human EML2 siRNA - orb268970 from Biorbyt
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EML2 shRNA Plasmid (Human) - CHH8468 from Cohesion Biosciences
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EML2 miRNA 3'UTR clone - MiUTR3H-14738 from Creative biogene
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