| Gene Symbol |
KCND1
|
| Entrez Gene |
3750
|
| Alt Symbol |
KV4.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage gated Shal related subfamily D, member 1
|
| Other Description |
Shal-type potassium channel|potassium voltage-gated channel subfamily D member 1|potassium voltage-gated channel, Shal-related subfamily, member 1|voltage-gated potassium channel subunit Kv4.1
|
| Swissprots |
O75671 B2RCG0 A6NEF1 Q9NSA2
|
| Accessions |
AAF65617 EAW50720 EAW50721 Q9NSA2 AB021865 BAA96454 AF166003 AAF65516 AJ005898 CAA06755 AK094431 BAG52865 AK315092 BAG37557 BC045659 AAH45659 XM_011543910 XP_011542212 NM_004979 NP_004970
|
| Function |
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain. {ECO:0000269|PubMed:10729221}.
|
![Western Blot: KCND1 Overexpression Lysate (Adult Normal) [NBL1-12145] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCND1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6081_KCND1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12145-img0002.jpg)