| Gene Symbol | Nes |
|---|---|
| Entrez Gene | 25491 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | nestin |
| Other Description | - |
| Swissprots | Q8CJ14 P21263 |
| Accessions | AAB64425 EDM00748 EDM00749 EDM00750 P21263 AF538924 AAN33053 M34384 AAA41685 XM_006232600 XP_006232662 NM_001308239 NP_001295168 NM_012987 NP_037119 |
| Function | Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. {ECO:0000250, ECO:0000269|PubMed:12686602, ECO:0000269|PubMed:20510364}. |
| Tissue Specificity | CNS stem cells. |
CompoZr® Knockout ZFN Kit - CKOZFN57900 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND57900 from Sigma-Aldrich
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NES siRNA (Rat) - CRR0718 from Cohesion Biosciences
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shRNA set against Rat Nes (NM_012987.1) - SHH351405 from Creative biogene
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nestin siRNA (r) - sc-156055 from Santa Cruz Biotechnology
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nestin shRNA Plasmid (r) - sc-156055-SH from Santa Cruz Biotechnology
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Rat NES siRNA - orb295567 from Biorbyt
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NES shRNA Plasmid (Rat) - CHR0718 from Cohesion Biosciences
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NES miRNA 3'UTR clone - MiUTR1R-04169 from Creative biogene
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